Formulary
Palonosetron with netupitant: Indications, Dosing, Side Effects and Interactions
Palonosetron with netupitant clinical drug profile including indications, dosing, side effects, cautions and interactions.
MedNext Academy | 3 min read
Palonosetron with netupitant: Indications, Dosing, Side Effects and Interactions
Palonosetron with netupitant clinical drug profile including indications, dosing, side effects, cautions and interactions.
Indications and dose
**Moderately emetogenic chemotherapy,Highly emetogenic cisplatin-based chemotherapy**
- **Adult** (By Mouth): 1 capsule, to be taken approximately 1 hour before the start of each chemotherapy cycle.
Cautions
For palonosetron with netupitant Patients over 75 years
Side effects
For palonosetron with netupitant Common or very common Asthenia; constipation; headache Uncommon Alopecia; cardiac conduction disorders; cardiomyopathy; diarrhoea; dizziness; flatulence; gastrointestinal discomfort; hiccups; hypertension; increased leucocytes; neutropenia; QT interval prolongation; sleep disorders; urticaria; vertigo Rare or very rare Acute psychosis; arrhythmias; conjunctivitis; cystitis; dysphagia; feeling hot; hypokalaemia; hypotension; leucopenia; mitral valve incompetence; mood altered; myocardial ischaemia; numbness; pain; tongue coated; vision blurred
Pregnancy
For palonosetron with netupitant Manufacturer advises avoid-toxicity in animal studies.
Breast feeding
For palonosetron with netupitant Manufacturer advises avoid during treatment and for 1 month after last dose-no information available.
Hepatic impairment
For palonosetron with netupitant Manufacturer advises caution in severe impairment (risk of increased exposure, limited information available).
Medicinal forms
Clinical governance
**Author:** MedNext Clinical Team. **Clinical reviewer:** Dr Shameer Deen, MBBS, MS, MRCS. **Sources:** BNF, Indian Pharmacopoeia, CIMS India. **Correction:** Report errors at support@mednext.academy.
Inside MedNext for this topic
- 411 MedNext-authored chapters
- 80,000+ MCQ bank
- 15 study modes
- Growing visual cheat sheets
Study modes
- Notes
- MCQ
- Audio
- Video
- Visual
- 3D Anatomy
- Trace
- Flashcards
- Mnemonics
- Image Bank
- Clinical
- Microscopy
- Audio QBank
- Cadaver
- Book Match
Continue reading
Subject HubPharmacology Hub
All pharmacology resources in one place.
Drug SchedulesIndian Drug Schedules
Schedule H, H1, X and G classifications.
FormularyBrowse all drugs
Search 1,850+ drug profiles.
Study Palonosetron with netupitant in the MedNext app
Challenge yourself with targeted pharmacology MCQs on this drug class. Every explanation links back to the chapter that teaches the concept.
Start drug challengeExplore the full formulary

