Formulary
Magnesium citrate: Indications, Dosing, Side Effects and Interactions
Magnesium citrate clinical drug profile including indications, dosing, side effects, cautions and interactions.
MedNext Academy | 3 min read
Magnesium citrate: Indications, Dosing, Side Effects and Interactions
Magnesium citrate clinical drug profile including indications, dosing, side effects, cautions and interactions.
Indications and dose
**Treatment and prevention of magnesium deficiency**
- **Adult** (By Mouth): 4-8 mmol 3 times a day.
**Treatment and prevention of magnesium deficiency for magnesium citrate**
- **Child 12-17 years** (By mouth): 4 mmol 3 times a day.
Cautions
Disorders of cardiac conduction
Side effects
Common or very common Diarrhoea (with high doses); faeces soft (with high doses) Rare or very rare Fatigue (long term use) Frequency not known Gastrointestinal irritation (with high doses)
Interactions
**Severe interactions:**
- Long-term treatment with proton pump inhibitors (e.g.
- Aminoglycoside antibiotics (e.g.
**Other interactions (6):**
- This specifically applies to: Cellulose sodium phosphate; edetate disodium : concurrent use with magnesium supplements may result in binding of magnesium; patients should be advised not to take...
- Magnesium homeostasis influenced by medication Because of increased magnesium losses, a dose adjustment of magnesium may be necessary when taking the following substances: Diuretics (e.g.
- VEGF-blockers Bevacizumab is a humanised IgG1 antibody that binds and inhibits VEGF activity.
- PD-1 inhibitors Nivolumab is a human IgG4 anti-PD-1 monoclonal antibody that works as a checkpoint inhibitor that allows the immune system to kill cancer cells.
- Other viral DNA polymerase inhibitors include Pentamidine, Rapamycin and Amphotericin B.
- Ciclosporin A and Tacrolimus) increase the loss of magnesium via the kidneys.
Renal impairment
Avoid in severe impairment. M
Medicinal forms
Clinical governance
**Author:** MedNext Clinical Team. **Clinical reviewer:** Dr Shameer Deen, MBBS, MS, MRCS. **Sources:** BNF, Indian Pharmacopoeia, CIMS India. **Correction:** Report errors at support@mednext.academy.
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