Formulary
Calcipotriol: Indications, Dosing, Side Effects and Interactions
Calcipotriol clinical drug profile including indications, dosing, side effects, cautions and interactions.
MedNext Academy | 3 min read
Calcipotriol: Indications, Dosing, Side Effects and Interactions
Calcipotriol clinical drug profile including indications, dosing, side effects, cautions and interactions.
Indications and dose
**Plaque psoriasis**
- **Adult** (To The Skin Using Ointment): Apply 1-2 times a day, when preparations are used together maximum total calcipotriol 5 mg in any one week (e.g. scalp solution 60 mL with ointment 30 g or scalp solution 30 mL with ointment 60 g); maximum 100 g per week.
**Scalp psoriasis**
- **Adult** (To The Skin Using Scalp Lotion): Apply twice daily, when preparations are used together maximum total calcipotriol 5 mg in any one week (e.g. scalp solution 60 mL with ointment 30 g or scalp solution 30 mL with ointment 60 g); maximum 60 mL per week.
**Plaque psoriasis for calcipotriol**
- **Child 6-11 years** (To the skin using ointment): Apply twice daily, when preparations used together maximum total calcipotriol 2.5 mg in any one week (e.g. scalp solution 20 mL with ointment 30 g); maximum 50 g per week.
- **Child 12-17 years** (To the skin using ointment): Apply twice daily, when preparations used together maximum total calcipotriol 3.75 mg in any one week (e.g. scalp solution 30 mL with ointment 45 g); maximum 75 g per week.
**Scalp psoriasis for calcipotriol**
- **Child 6-11 years (specialist use only)** (To the skin using scalp lotion): Apply twice daily, when preparations used together max. total calcipotriol 2.5 mg in any one week (e.g. scalp solution 20 mL with ointment 30 g); maximum 30 mL per week.
- **Child 12-17 years (specialist use only)** (To the skin using scalp lotion): Apply twice daily, when preparations used together maximum total calcipotriol 3.75 mg in any one week (e.g. scalp solution 30 mL with ointment 45 g); maximum 45 mL per week.
Cautions
Avoid excessive exposure to sunlight and sunlamps; avoid use on face; erythrodermic exfoliative psoriasis (enhanced risk of hypercalcaemia); generalised pustular psoriasis (enhanced risk of hypercalcaemia)
Contraindications
Calcium metabolism disorders
Side effects
Common or very common Skin reactions Uncommon Hypercalcaemia; increased risk of infection Rare or very rare Hypercalciuria; photosensitivity reaction
Interactions
**Severe interactions:**
- Concomitant use with systemic vitamin D products, calcium supplements, or other agents that can increase serum calcium concentrations such as thiazide diuretics, oestrogens, anabolic steroids, and...
Pregnancy
Manufacturers advise avoid unless essential.
Breast feeding
No information available.
Hepatic impairment
Manufacturers advise avoid in severe impairment (no information available).
Renal impairment
Avoid in severe impairment (no information available). M
Medicinal forms
Ointment,Solution
Clinical governance
**Author:** MedNext Clinical Team. **Clinical reviewer:** Dr Shameer Deen, MBBS, MS, MRCS. **Sources:** BNF, Indian Pharmacopoeia, CIMS India. **Correction:** Report errors at support@mednext.academy.
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