Read the slide
Histology - Image Library
Haematoxylin and eosin slides annotated with the structures and the features that separate benign from malignant.
- Structures labelled
- Annotated
- Teaching points
- H&E
What's inside the Histology library
The histology library links what you see down the microscope to the diagnosis - architecture first, then cytology - with the malignant features called out explicitly.
Colonic adenocarcinoma
Malignant glands are irregular, crowded and back-to-back, often with cribriform (gland-within-gland) architecture, lined by cells with enlarged, elongated, hyperchromatic and stratified nuclei and a raised nuclear-to-cytoplasmic ratio. The gland-forming pattern defines an adenocarcinoma; invasion through the muscularis mucosae into the stroma, with a desmoplastic reaction, is what separates invasive carcinoma from high-grade dysplasia.
Move from low power to the decisive detail
At low power, orient the tissue and assess architecture, compartment and distribution. At intermediate power, compare cellularity, stroma, inflammation, necrosis and vascular change. Only then use high power for nuclear and cytoplasmic detail, organisms or mitoses. Keep a short differential until the pattern, clinical context and any stains support a conclusion. Digital teaching fields are selected views and may not represent the whole slide; exam recognition is valuable, but diagnostic reporting requires complete material, quality control and appropriately trained pathology review.
Work through the full Histology library in MedNext
Every image is annotated the same way, mapped to high-yield exam topics and linked to its chapter.
Compare MedNext plans