Formulary
Vismodegib [Specialist drug]: Indications, Dosing, Side Effects and Interactions
Vismodegib [Specialist drug] clinical drug profile including indications, dosing, side effects, cautions and interactions.
MedNext Academy | 3 min read
Vismodegib [Specialist drug]: Indications, Dosing, Side Effects and Interactions
Vismodegib [Specialist drug] clinical drug profile including indications, dosing, side effects, cautions and interactions.
Indications and dose
**Basal cell carcinoma**
- **Adult** (By Mouth): Specialist drug - access specialist resources for dosing information.
Side effects
For vismodegib [Specialist drug] Common or very common Alopecia; amenorrhoea; appetite decreased; arthralgia; asthenia; constipation; dehydration; diarrhoea; gastrointestinal discomfort; hair growth abnormal; muscle complaints; nausea; pain; skin reactions; taste altered; vomiting; weight decreased Frequency not known Epiphyses premature fusion
Pregnancy
Important safety information For vismodegib [Specialist drug] Risks of incorrect dosing of oral anti-cancer medicines See Cytotoxic drugs . Pregnancy Prevention Programme Important: teratogenic risk -may cause severe birth defects and embryo-fetal death. Prescribers and pharmacists must comply with prescribing and dispensing restrictions as specified in the manufacturer's Pregnancy Prevention Programme, and ensure that the patient fully acknowledges the programme's pregnancy prevention measures-consult product literature for further information.
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Clinical governance
**Author:** MedNext Clinical Team. **Clinical reviewer:** Dr Shameer Deen, MBBS, MS, MRCS. **Sources:** BNF, Indian Pharmacopoeia, CIMS India. **Correction:** Report errors at support@mednext.academy.
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