Formulary
Vindesine sulfate [Specialist drug]: Indications, Dosing, Side Effects and Interactions
Vindesine sulfate [Specialist drug] clinical drug profile including indications, dosing, side effects, cautions and interactions.
MedNext Academy | 3 min read
Vindesine sulfate [Specialist drug]: Indications, Dosing, Side Effects and Interactions
Vindesine sulfate [Specialist drug] clinical drug profile including indications, dosing, side effects, cautions and interactions.
Indications and dose
**Variety of cancers including leukaemias, lymphomas, and some solid tumours (e.g. breast and lung cancer)**
- **Adult** (By Intravenous Injection): Specialist drug - access specialist resources for dosing information.
Contraindications
For vindesine sulfate [Specialist drug] Contra-indications, further information Intrathecal injection contra-indicated .
Side effects
For vindesine sulfate [Specialist drug] Common or very common Alopecia Frequency not known Anaemia; appetite decreased; asthenia; balance impaired; cellulitis; chills; constipation; depression; diarrhoea; dizziness; dysphagia; fever; gastrointestinal discomfort; gastrointestinal disorders; granulocytopenia (dose-limiting); headache; hearing impairment; malaise; nausea; nerve disorders; nystagmus; oral disorders; pain; peroneal nerve palsy; rash maculopapular; reflexes absent; seizure; sensation abnormal; thrombocytopenia; thrombocytosis; vertigo; vestibular damage; vision loss; vomiting Side-effects, further information Neurotoxicity, usually as peripheral or autonomic neuropathy; it occurs less often with vindesine than with vincristine. Patients with neurotoxicity commonly have peripheral paraesthesia, loss of deep tendon reflexes; and ototoxicity has been reported. There have been instances in which neurotoxicity has made it necessary to reduce the dosage or temporarily discontinue use of vindesine.
Medicinal forms
Clinical governance
**Author:** MedNext Clinical Team. **Clinical reviewer:** Dr Shameer Deen, MBBS, MS, MRCS. **Sources:** BNF, Indian Pharmacopoeia, CIMS India. **Correction:** Report errors at support@mednext.academy.
Inside MedNext for this topic
- 411 MedNext-authored chapters
- 80,000+ MCQ bank
- 15 study modes
- Growing visual cheat sheets
Study modes
- Notes
- MCQ
- Audio
- Video
- Visual
- 3D Anatomy
- Trace
- Flashcards
- Mnemonics
- Image Bank
- Clinical
- Microscopy
- Audio QBank
- Cadaver
- Book Match
Continue reading
Subject HubPharmacology Hub
All pharmacology resources in one place.
Drug SchedulesIndian Drug Schedules
Schedule H, H1, X and G classifications.
FormularyBrowse all drugs
Search 1,850+ drug profiles.
Study Vindesine sulfate [Specialist drug] in the MedNext app
Challenge yourself with targeted pharmacology MCQs on this drug class. Every explanation links back to the chapter that teaches the concept.
Start drug challengeExplore the full formulary

