Formulary
Urofollitropin: Indications, Dosing, Side Effects and Interactions
Urofollitropin is purified extract of human post-menopausal urine containing follicle-stimulating hormone (FSH).
MedNext Academy | 3 min read
Urofollitropin: Indications, Dosing, Side Effects and Interactions
Urofollitropin is purified extract of human post-menopausal urine containing follicle-stimulating hormone (FSH).
Drug action
Urofollitropin is purified extract of human post-menopausal urine containing follicle-stimulating hormone (FSH).
Indications and dose
**Infertility in women with proven hypopituitarism or who have not responded to clomifene,Superovulation treatment**
- **Adult** (By Subcutaneous Injection, Or By Deep Intramuscular Injection): for assisted conception (such as in vitro fertilisation) (female) Adjusted according to response.
Cautions
Acute porphyrias
Contraindications
Ovarian cysts (not caused by polycystic ovarian syndrome); tumours of breast; tumours of hypothalamus; tumours of ovaries; tumours of pituitary; tumours of uterus; vaginal bleeding of unknown cause
Side effects
Common or very common Breast tenderness; constipation; diarrhoea; gastrointestinal discomfort; headache; hot flush; increased risk of infection; muscle spasms; nausea; ovarian hyperstimulation syndrome; pain; pelvic pain; rash; vaginal discharge; vaginal haemorrhage; vomiting
Pregnancy
Avoid.
Breast feeding
Avoid.
Medicinal forms
Clinical governance
**Author:** MedNext Clinical Team. **Clinical reviewer:** Dr Shameer Deen, MBBS, MS, MRCS. **Sources:** BNF, Indian Pharmacopoeia, CIMS India. **Correction:** Report errors at support@mednext.academy.
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