Formulary
Umeclidinium with vilanterol: Indications, Dosing, Side Effects and Interactions
Umeclidinium with vilanterol clinical drug profile including indications, dosing, side effects, cautions and interactions.
MedNext Academy | 3 min read
Umeclidinium with vilanterol: Indications, Dosing, Side Effects and Interactions
Umeclidinium with vilanterol clinical drug profile including indications, dosing, side effects, cautions and interactions.
Indications and dose
**Maintenance treatment of chronic obstructive pulmonary disease**
- **Adult** (By Inhalation Of Powder): 1 inhalation once daily.
Cautions
For all beta-2-adrenoceptor agonists, selective Arrhythmias; cardiovascular disease; diabetes (risk of hyperglycaemia and ketoacidosis, especially with intravenous use); hypertension; hyperthyroidism; hypokalaemia; susceptibility to QT-interval prolongation Cautions, further information Hypokalaemia Potentially serious hypokalaemia may result from beta 2 agonist therapy. Particular caution is required in severe asthma or COPD, because this effect may be potentiated by concomitant treatment with theophylline and its derivatives, corticosteroids, diuretics, and by hypoxia. M
Side effects
For all beta-2-adrenoceptor agonists, selective Common or very common Arrhythmias; dizziness; headache; hyperglycaemia; palpitations; tremor Rare or very rare Bronchospasm paradoxical (sometimes severe) Side-effects For umeclidinium with vilanterol Common or very common Constipation; dry mouth; oropharyngeal pain; sinusitis Uncommon Dysphonia; taste altered Rare or very rare Glaucoma; urinary disorders; vision blurred
Pregnancy
For all beta-2-adrenoceptor agonists, selective Inhaled drugs for asthma can be taken as normal during pregnancy.
Medicinal forms
Clinical governance
**Author:** MedNext Clinical Team. **Clinical reviewer:** Dr Shameer Deen, MBBS, MS, MRCS. **Sources:** BNF, Indian Pharmacopoeia, CIMS India. **Correction:** Report errors at support@mednext.academy.
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