Formulary
Tretinoin with clindamycin: Indications, Dosing, Side Effects and Interactions
Tretinoin with clindamycin clinical drug profile including indications, dosing, side effects, cautions and interactions.
MedNext Academy | 3 min read
Tretinoin with clindamycin: Indications, Dosing, Side Effects and Interactions
Tretinoin with clindamycin clinical drug profile including indications, dosing, side effects, cautions and interactions.
Indications and dose
**Acne vulgaris**
- **Child** (To The Skin): 12-17 years Apply once daily, to be applied thinly at bedtime.
- **Adult** (To The Skin): Apply once daily, to be applied thinly at bedtime.
**Acne vulgaris for tretinoin with clindamycin**
- **Child 12-17 years** (To the skin): Apply once daily, to be applied thinly at bedtime.
Cautions
For tretinoin with clindamycin Allow peeling (resulting from other irritant treatments) to subside before using a topical retinoid; avoid accumulation in angles of the nose; avoid contact with eyes, nostrils, mouth and mucous membranes, eczematous, broken or sunburned skin; avoid exposure to UV light (including sunlight, solariums); avoid use of topical retinoids with keratolytic agents, abrasive cleaners, comedogenic or astringent cosmetics; caution in sensitive areas such as the neck; severe acne
Contraindications
For tretinoin with clindamycin Perioral dermatitis; personal or familial history of skin cancer; rosacea
Side effects
For tretinoin with clindamycin Frequency not known Dry skin (discontinue if severe); eye irritation; oedema; photosensitivity reaction; skin pigmentation change (transient); skin reactions
Pregnancy
For tretinoin with clindamycin The MHRA advises that systemic exposure is thought to be negligible following application of topical retinoids. However, since risk cannot be excluded, use of topical retinoids is contraindicated during pregnancy as a precaution.
Breast feeding
For tretinoin with clindamycin With topical use: Amount of drug in milk after topical application probably too small to be harmful; ensure infant does not come in contact with treated areas.
Medicinal forms
Clinical governance
**Author:** MedNext Clinical Team. **Clinical reviewer:** Dr Shameer Deen, MBBS, MS, MRCS. **Sources:** BNF, Indian Pharmacopoeia, CIMS India. **Correction:** Report errors at support@mednext.academy.
Inside MedNext for this topic
- 411 MedNext-authored chapters
- 80,000+ MCQ bank
- 15 study modes
- Growing visual cheat sheets
Study modes
- Notes
- MCQ
- Audio
- Video
- Visual
- 3D Anatomy
- Trace
- Flashcards
- Mnemonics
- Image Bank
- Clinical
- Microscopy
- Audio QBank
- Cadaver
- Book Match
Continue reading
Subject HubPharmacology Hub
All pharmacology resources in one place.
Drug SchedulesIndian Drug Schedules
Schedule H, H1, X and G classifications.
FormularyBrowse all drugs
Search 1,850+ drug profiles.
Study Tretinoin with clindamycin in the MedNext app
Challenge yourself with targeted pharmacology MCQs on this drug class. Every explanation links back to the chapter that teaches the concept.
Start drug challengeExplore the full formulary

