Formulary
Trastuzumab emtansine [Specialist drug]: Indications, Dosing, Side Effects and Interactions
Trastuzumab emtansine [Specialist drug] clinical drug profile including indications, dosing, side effects, cautions and interactions.
MedNext Academy | 3 min read
Trastuzumab emtansine [Specialist drug]: Indications, Dosing, Side Effects and Interactions
Trastuzumab emtansine [Specialist drug] clinical drug profile including indications, dosing, side effects, cautions and interactions.
Indications and dose
**Breast cancer**
- **Adult** (By Intravenous Infusion): Specialist drug - access specialist resources for dosing information.
Side effects
For trastuzumab emtansine [Specialist drug] Common or very common Alopecia; anaemia; arthralgia; asthenia; chills; conjunctivitis; constipation; cough; diarrhoea; dizziness; dry eye; dry mouth; dyspnoea; excessive tearing; fever; gastrointestinal discomfort; haemorrhage; headache; hypersensitivity; hypertension; hypokalaemia; infusion related reaction; insomnia; left ventricular dysfunction; leucopenia; memory loss; musculoskeletal pain; myalgia; nail disorder; nausea; neutropenia; peripheral neuropathy; peripheral oedema; skin reactions; stomatitis; taste altered; thrombocytopenia; urinary tract infection; vision blurred; vomiting Uncommon Hepatic disorders; nodular regenerative hyperplasia; pneumonitis Side-effects, further information Heart failure Delay or discontinue treatment in cases of left ventricular dysfunction; discontinue treatment if symptomatic heart failure occurs. Interstitial lung disease and pneumonitis Interstitial lung disease and pneumonitis, including fatal events, have been reported; if confirmed treatment should be discontinued. Peripheral neuropathy Temporarily discontinue treatment if peripheral neuropathy occurs; if restarting, consider dose adjustment.
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Clinical governance
**Author:** MedNext Clinical Team. **Clinical reviewer:** Dr Shameer Deen, MBBS, MS, MRCS. **Sources:** BNF, Indian Pharmacopoeia, CIMS India. **Correction:** Report errors at support@mednext.academy.
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