Formulary
Tirbanibulin: Indications, Dosing, Side Effects and Interactions
Tirbanibulin is a tyrosine kinase inhibitor which binds to tubulin thereby inducing death of proliferating cells.
MedNext Academy | 3 min read
Tirbanibulin: Indications, Dosing, Side Effects and Interactions
Tirbanibulin is a tyrosine kinase inhibitor which binds to tubulin thereby inducing death of proliferating cells.
Drug action
Tirbanibulin is a tyrosine kinase inhibitor which binds to tubulin thereby inducing death of proliferating cells.
Indications and dose
**Actinic keratosis on face or scalp**
- **Adult** (To The Skin): Apply once daily for 5 consecutive days, consider other treatment options if treated area does not show complete clearance after about 8 weeks.
Cautions
Avoid contact with eyes; avoid contact with inside of ears; avoid contact with inside of nostrils; avoid contact with lips; avoid contact with open wounds or broken skin; avoid occlusive dressings on treated area; immunocompromised patients
Side effects
Frequency not known Skin eruption localised
Interactions
**Other interactions (1):**
- Given the route of administration (topical), the short duration of dosing (5 days), the low systemic exposure (subnanomolar mean C max ), and the in vitro data, there is low potential for...
Pregnancy
Avoid-toxicity in animal studies. M
Breast feeding
Specialist sources indicate use with caution-amount in milk is likely to be low. Do not apply to breast or nipple and avoid contact with infant's skin.
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Clinical governance
**Author:** MedNext Clinical Team. **Clinical reviewer:** Dr Shameer Deen, MBBS, MS, MRCS. **Sources:** BNF, Indian Pharmacopoeia, CIMS India. **Correction:** Report errors at support@mednext.academy.
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