Formulary
Thyrotropin alfa: Indications, Dosing, Side Effects and Interactions
Thyrotropin alfa is a recombinant form of thyrotrophin (human thyroid stimulating hormone).
MedNext Academy | 3 min read
Thyrotropin alfa: Indications, Dosing, Side Effects and Interactions
Thyrotropin alfa is a recombinant form of thyrotrophin (human thyroid stimulating hormone).
Drug action
Thyrotropin alfa is a recombinant form of thyrotrophin (human thyroid stimulating hormone). .
Indications and dose
**Detection of thyroid remnants and thyroid cancer in post-thyroidectomy patients, together with serum thyroglobulin testing (with or without radioiodine imaging),To increase radio-iodine uptake**
- **Adult** (By Intramuscular Injection): for the ablation of thyroid remnant tissue in suitable post-thyroidectomy patients 900 micrograms every 24 hours for 2 doses, dose to be administered into the gluteal muscle, consult product literature for further information on indications and dose.
Cautions
Presence of thyroglobulin autoantibodies may give false negative results
Side effects
Common or very common Asthenia; dizziness; headache; nausea; vomiting Uncommon Chills; diarrhoea; feeling hot; fever; flushing; hypersensitivity; influenza; influenza like illness; pain; paraesthesia; pulmonary reaction; skin reactions; taste altered Rare or very rare Atrial fibrillation; hyperthyroidism Frequency not known Arthralgia; dyspnoea; goitre; hyperhidrosis; myalgia; neoplasm complications; palpitations; residual metastases enlarged; stroke; tremor
Pregnancy
Avoid.
Breast feeding
Avoid.
Medicinal forms
Clinical governance
**Author:** MedNext Clinical Team. **Clinical reviewer:** Dr Shameer Deen, MBBS, MS, MRCS. **Sources:** BNF, Indian Pharmacopoeia, CIMS India. **Correction:** Report errors at support@mednext.academy.
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