Formulary
Thiotepa [Specialist drug]: Indications, Dosing, Side Effects and Interactions
Thiotepa [Specialist drug] clinical drug profile including indications, dosing, side effects, cautions and interactions.
MedNext Academy | 3 min read
Thiotepa [Specialist drug]: Indications, Dosing, Side Effects and Interactions
Thiotepa [Specialist drug] clinical drug profile including indications, dosing, side effects, cautions and interactions.
Indications and dose
**Conditioning treatment before haematopoietic stem cell transplantation in the treatment of haematological disease or solid tumours**
- **Adult** (By Intravenous Infusion): Specialist drug - access specialist resources for dosing information.
Contraindications
For thiotepa [Specialist drug] Acute porphyrias
Side effects
For thiotepa [Specialist drug] Common or very common Alopecia; amenorrhoea; anaemia; anxiety; appetite decreased; arrhythmias; arthralgia; asthenia; azoospermia; cataract; chills; cognitive disorder; confusion; conjunctivitis; constipation; cough; cystitis; delirium; diarrhoea; dizziness; dysuria; embolism; encephalopathy; extrapyramidal symptoms; fever; gastrointestinal discomfort; gastrointestinal disorders; generalised oedema; graft versus host disease; haemorrhage; headache; hearing impairment; heart failure; hepatic disorders; hyperglycaemia; hypersensitivity; hypertension; hypopituitarism; increased risk of infection; infertility; interstitial lung disease; intracranial aneurysm; intracranial haemorrhage; leucopenia; lymphoedema; menopausal symptoms; mucositis; multi organ failure; myalgia; nausea; neutropenia; ototoxicity; pain; pancytopenia; paraesthesia; psychiatric disorder; pulmonary oedema; renal impairment; secondary malignancy; seizure; sepsis; sinusoidal obstruction syndrome; skin reactions; stomatitis; thrombocytopenia; toxic shock syndrome; vision blurred; vomiting; weight increased Uncommon Cardiomyopathy; hallucination; hypoxia; myocarditis Frequency not known Severe cutaneous adverse reactions (SCARs)
Medicinal forms
Clinical governance
**Author:** MedNext Clinical Team. **Clinical reviewer:** Dr Shameer Deen, MBBS, MS, MRCS. **Sources:** BNF, Indian Pharmacopoeia, CIMS India. **Correction:** Report errors at support@mednext.academy.
Inside MedNext for this topic
- 411 MedNext-authored chapters
- 80,000+ MCQ bank
- 15 study modes
- Growing visual cheat sheets
Study modes
- Notes
- MCQ
- Audio
- Video
- Visual
- 3D Anatomy
- Trace
- Flashcards
- Mnemonics
- Image Bank
- Clinical
- Microscopy
- Audio QBank
- Cadaver
- Book Match
Continue reading
Subject HubPharmacology Hub
All pharmacology resources in one place.
Drug SchedulesIndian Drug Schedules
Schedule H, H1, X and G classifications.
FormularyBrowse all drugs
Search 1,850+ drug profiles.
Study Thiotepa [Specialist drug] in the MedNext app
Challenge yourself with targeted pharmacology MCQs on this drug class. Every explanation links back to the chapter that teaches the concept.
Start drug challengeExplore the full formulary

