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Teriparatide: Indications, Dosing, Side Effects and Interactions
Teriparatide clinical drug profile including indications, dosing, side effects, cautions and interactions.
MedNext Academy | 3 min read
Teriparatide: Indications, Dosing, Side Effects and Interactions
Teriparatide clinical drug profile including indications, dosing, side effects, cautions and interactions.
Indications and dose
**Treatment of osteoporosis in postmenopausal women and in men at increased risk of fractures,Treatment of corticosteroid-induced osteoporosis**
- **Adult** (By Subcutaneous Injection): 20 micrograms daily for maximum duration of treatment 24 months (course not to be repeated).
Contraindications
Bone metastases; hyperparathyroidism; metabolic bone diseases; Paget's disease; pre-existing hypercalcaemia; previous radiation therapy to the skeleton; skeletal malignancies; unexplained raised alkaline phosphatase
Side effects
Common or very common Anaemia; asthenia; chest pain; depression; dizziness; dyspnoea; gastrointestinal disorders; headache; hypercholesterolaemia; hyperhidrosis; hypotension; muscle complaints; nausea; pain; palpitations; sciatica; syncope; vertigo; vomiting Uncommon Arthralgia; emphysema; hypercalcaemia; hyperuricaemia; nephrolithiasis; tachycardia; urinary disorders; weight increased Rare or very rare Oedema; renal impairment; urticaria generalised
Interactions
**Other interactions (2):**
- In a study of 15 healthy subjects administered digoxin daily to steady state, a single FORSTEO dose did not alter the cardiac effect of digoxin.
- FORSTEO has been evaluated in pharmacodynamic interaction studies with hydrochlorothiazide.
Pregnancy
Avoid.
Breast feeding
Avoid.
Renal impairment
Caution in moderate impairment; avoid if severe. M
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Clinical governance
**Author:** MedNext Clinical Team. **Clinical reviewer:** Dr Shameer Deen, MBBS, MS, MRCS. **Sources:** BNF, Indian Pharmacopoeia, CIMS India. **Correction:** Report errors at support@mednext.academy.
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