Formulary
Talimogene laherparepvec [Specialist drug]: Indications, Dosing, Side Effects and Interactions
Talimogene laherparepvec [Specialist drug] clinical drug profile including indications, dosing, side effects, cautions and interactions.
MedNext Academy | 3 min read
Talimogene laherparepvec [Specialist drug]: Indications, Dosing, Side Effects and Interactions
Talimogene laherparepvec [Specialist drug] clinical drug profile including indications, dosing, side effects, cautions and interactions.
Contraindications
For talimogene laherparepvec [Specialist drug] Severely immunocompromised patients Contra-indications, further information Manufacturer advises avoid in patients who are severely immunocompromised, for example, those with severe congenital or acquired cellular and/or humoral immune deficiency-may be at increased risk of disseminated herpetic infection.
Side effects
For talimogene laherparepvec [Specialist drug] Common or very common Anaemia; anxiety; arthralgia; chills; confusion; constipation; cough; deep vein thrombosis; dehydration; depression; diarrhoea; dizziness; dyspnoea; ear pain; fatigue; fever; flushing; gastrointestinal discomfort; headache; hypertension; immune-mediated events; increased risk of infection; influenza like illness; insomnia; malaise; myalgia; nausea; neoplasm complications; oropharyngeal pain; pain; peripheral oedema; procedural pain; secretion discharge; skin reactions; tachycardia; vomiting; weight decreased; wound complications Uncommon Glomerulonephritis; injection site plasmacytoma; obstructive airway disorder; pneumonitis; post procedural infection; vasculitis Side-effects, further information Necrosis or ulceration of tumour tissue may occur, and impaired healing at the injection site has been reported. Manufacturer advises careful wound care and infection precautions; if persistent infection or delayed healing develops, the risks and benefits of continuing treatment should be considered.
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Clinical governance
**Author:** MedNext Clinical Team. **Clinical reviewer:** Dr Shameer Deen, MBBS, MS, MRCS. **Sources:** BNF, Indian Pharmacopoeia, CIMS India. **Correction:** Report errors at support@mednext.academy.
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