Formulary
Sodium feredetate: Indications, Dosing, Side Effects and Interactions
Sodium feredetate clinical drug profile including indications, dosing, side effects, cautions and interactions.
MedNext Academy | 3 min read
Sodium feredetate: Indications, Dosing, Side Effects and Interactions
Sodium feredetate clinical drug profile including indications, dosing, side effects, cautions and interactions.
Indications and dose
**Iron-deficiency anaemia [treatment and prophylaxis]**
- **Adult** (By Mouth Using Oral Solution): 10-15 mL once daily, reduced if not tolerated to 10-15 mL once daily on alternate days.
**Iron-deficiency anaemia [treatment and prophylaxis] for sodium feredetate**
- **Neonate** (By mouth using oral solution): 1.5 mL once daily, reduced if not tolerated to 1.5 mL once daily on alternate days.
- **Child 1-11 months** (By mouth using oral solution): 2 mL once daily, reduced if not tolerated to 2 mL once daily on alternate days.
- **Child 1-4 years** (By mouth using oral solution): 4 mL once daily, reduced if not tolerated to 4 mL once daily on alternate days.
- **Child 5-11 years** (By mouth using oral solution): 8 mL once daily, reduced if not tolerated to 8 mL once daily on alternate days.
- **Child 12-17 years** (By mouth using oral solution): 10-15 mL once daily, reduced if not tolerated to 10-15 mL once daily on alternate days.
**Iron-deficiency anaemia [prophylaxis in preterm or low birth-weight babies who are solely or partially breast-fed] for sodium feredetate**
- **Neonate** (By mouth using oral solution): 0.5-1 mL once daily, supplementation is usually started 2-6 weeks after birth.
- **Child 1-11 months** (By mouth using oral solution): 0.5-1 mL once daily, supplementation is usually started 2-6 weeks after birth and continued for 6-12 months or until receiving sufficient iron-rich formula, dose can be increased if necessary to 2 mL once daily.
Cautions
For all iron (oral) High doses in elderly Cautions, further information Elderly Screening Tool of Older Persons' potentially inappropriate Prescriptions (STOPP) criteria to aid medication reviews (see Prescribing in the elderly for information): potentially inappropriate at oral doses greater than 200 mg elemental iron daily (no evidence of enhanced iron absorption above these doses).
Side effects
For all iron (oral) Common or very common Constipation; diarrhoea; gastrointestinal discomfort; nausea Uncommon Vomiting Frequency not known Appetite decreased; gastrointestinal disorders Side-effects, further information Iron can be constipating and occasionally lead to faecal impaction. Oral iron, particularly modified-release preparations, can exacerbate diarrhoea in patients with inflammatory bowel disease; care is also needed in patients with intestinal strictures and diverticular disease. Overdose For details on the management of poisoning, see Iron salts, under Emergency treatment of poisoning .
Medicinal forms
Clinical governance
**Author:** MedNext Clinical Team. **Clinical reviewer:** Dr Shameer Deen, MBBS, MS, MRCS. **Sources:** BNF, Indian Pharmacopoeia, CIMS India. **Correction:** Report errors at support@mednext.academy.
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