Formulary
Sodium acid phosphate with sodium phosphate: Indications, Dosing, Side Effects and Interactions
Sodium acid phosphate with sodium phosphate clinical drug profile including indications, dosing, side effects, cautions and interactions.
MedNext Academy | 4 min read
Sodium acid phosphate with sodium phosphate: Indications, Dosing, Side Effects and Interactions
Sodium acid phosphate with sodium phosphate clinical drug profile including indications, dosing, side effects, cautions and interactions.
Indications and dose
**Constipation (using Phosphates Enema BP Formula B),Bowel evacuation before abdominal radiological procedures, endoscopy, and surgery (using Phosphates Enema BP Formula B)**
- **Child** (By Rectum): 12-17 years 100-128 mL once daily.
- **Adult** (By Rectum): 128 mL daily.
**Constipation, using Phosphates Enema BP Formula B (dose approved**
- **Child** (By Rectum): for use by community practitioner nurse prescribers) 3-17 years Reduced according to body-weight.
- **Adult** (By Rectum): 128 mL daily.
**Constipation, using Phosphates Enema (Cleen Ready-to-Use) (dose approved**
- **Child** (By Rectum): 12-17 years 118 mL.
- **Adult** (By Rectum): 118 mL.
**Constipation,Bowel evacuation before abdominal radiological procedures,Bowel evacuation before endoscopy,Bowel evacuation before surgery**
- **Adult** (By Rectum): 118 mL.
**Bowel evacuation before colonic surgery,Bowel evacuation before colonoscopy,Bowel evacuation before radiological examination**
- **Adult** (By Mouth): 45 mL twice daily, each dose must be diluted with half a glass (120 mL) of cold water, followed by one full glass (240 mL) of cold water, timing of doses is dependent on the time of the procedure, for morning procedure, the first dose should be taken at 7 a.m. and second at 7 p.m. on day before the procedure; for afternoon procedure, first dose should be taken at 7 p.m. on day before and second dose at 7 a.m. on day of the procedure.
**Constipation (using Phosphates Enema BP Formula B), Bowel evacuation before abdominal radiological procedures, endoscopy, and surgery (using Phosphates Enema BP Formula B) for sodium acid phosphate with sodium phosphate**
- **Child 3-6 years** (By rectum): 45-65 mL once daily.
- **Child 7-11 years** (By rectum): 65-100 mL once daily.
- **Child 12-17 years** (By rectum): 100-128 mL once daily.
**Constipation, using Phosphates Enema BP Formula B (dose approved for use by community practitioner nurse prescribers) for sodium acid phosphate with sodium phosphate**
- **Child 3-17 years** (By rectum): Reduced according to body-weight.
**Constipation, using Phosphates Enema (Cleen Ready-to-Use) (dose approved for use by community practitioner nurse prescribers) for sodium acid phosphate with sodium phosphate**
- **Child 3-11 years** (By rectum): On doctor's advice only.
- **Child 12-17 years** (By rectum): 118 mL.
**Constipation, Bowel evacuation before abdominal radiological procedures, Bowel evacuation before endoscopy, Bowel evacuation before surgery for Fleet ready-to-use enema**
- **Child 3-6 years** (By rectum): 40-60 mL once daily.
- **Child 7-11 years** (By rectum): 60-90 mL once daily.
- **Child 12-17 years** (By rectum): 90-118 mL once daily.
Cautions
For sodium acid phosphate with sodium phosphate With oral use Cardiac disease (in adults); colitis (in adults); debilitated patients (in adults); elderly (in adults); fluid and electrolyte disturbances (in adults); hypovolaemia (should be corrected before administration) (in adults) With rectal use Ascites; congestive heart failure; debilitated patients; elderly (in adults); fluid and electrolyte disturbances; uncontrolled hypertension
Contraindications
For sodium acid phosphate with sodium phosphate With oral use Acute severe colitis (in adults); ascites (in adults); congestive cardiac failure (in adults); gastric retention (in adults); gastro-intestinal obstruction (in adults); gastro-intestinal perforation (in adults); toxic megacolon (in adults) With rectal use Conditions associated with increased colonic absorption; gastro-intestinal obstruction; inflammatory bowel disease
Side effects
For sodium acid phosphate with sodium phosphate General side-effects: Common or very common Chills; gastrointestinal discomfort; nausea; vomiting Uncommon Dehydration Rare or very rare Electrolyte imbalance; metabolic acidosis Specific side-effects: Common or very common With oral use Asthenia (in adults); chest pain (in adults); dizziness (in adults); headache (in adults) Rare or very rare With oral use Allergic dermatitis (in adults); arrhythmia (in adults); hypotension (in adults); loss of consciousness (in adults); muscle cramps (in adults); myocardial infarction (in adults); nephrocalcinosis (in adults); paraesthesia (in adults); renal impairment (in adults); tetany (in adults) With rectal use Pain
Pregnancy
For sodium acid phosphate with sodium phosphate With oral use in adults: Caution.
Breast feeding
For sodium acid phosphate with sodium phosphate With oral use in adults: Caution.
Renal impairment
For sodium acid phosphate with sodium phosphate With oral use in adults: Avoid. M With rectal use: Caution; avoid in significant impairment. M
Medicinal forms
Solution
Clinical governance
**Author:** MedNext Clinical Team. **Clinical reviewer:** Dr Shameer Deen, MBBS, MS, MRCS. **Sources:** BNF, Indian Pharmacopoeia, CIMS India. **Correction:** Report errors at support@mednext.academy.
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