Formulary
Serplulimab [Specialist drug]: Indications, Dosing, Side Effects and Interactions
Serplulimab [Specialist drug] clinical drug profile including indications, dosing, side effects, cautions and interactions.
MedNext Academy | 3 min read
Serplulimab [Specialist drug]: Indications, Dosing, Side Effects and Interactions
Serplulimab [Specialist drug] clinical drug profile including indications, dosing, side effects, cautions and interactions.
Indications and dose
**Small cell lung cancer**
- **Adult** (By Intravenous Infusion): Specialist drug - access specialist resources for dosing information.
Side effects
For serplulimab [Specialist drug] Common or very common Alopecia; anaemia; appetite decreased; arrhythmias; arthralgia; asthenia; cardiac conduction disorders; chest pain; constipation; cough; decreased leucocytes; diabetic ketoacidosis; diarrhoea; dizziness; dysphagia; dyspnoea; electrolyte imbalance; endocrine disorders; facial swelling; fever; gastrointestinal discomfort; gastrointestinal disorders; glucose tolerance impaired; glycosuria; haemorrhage; headache; heart failure; hepatic disorders; hyperbilirubinaemia; hyperglycaemia; hyperhidrosis; hyperlipidaemia; hypersensitivity; hypertension; hyperthyroidism; hyperuricaemia; hypoglycaemia; hypoproteinaemia; hypothyroidism; immune-mediated lung disease; increased risk of infection; inflammation; infusion related reaction; insomnia; interstitial lung disease; ketoacidosis; malaise; muscle weakness; musculoskeletal discomfort; myalgia; nausea; nerve disorders; neutropenia; oedema; oral disorders; pain; paraesthesia; QT interval prolongation; renal impairment; skin reactions; thrombocytopenia; thyroiditis; type 1 diabetes mellitus; vasculitis; vomiting; weight decreased Uncommon Adrenal insufficiency; arthritis; cardiac inflammation; cardiomyopathy; chills; dry mouth; encephalitis non-infective; euthyroid sick syndrome; hyperadrenocorticism; hypophysitis; immune-mediated pancreatitis; lymphadenitis; motor dysfunction; myocardial ischaemia; myopathy; neurotoxicity; pericardial effusion; sepsis; vertigo; vision blurred Frequency not known Acute coronary syndrome; cardiotoxicity; cholangitis acute; immune-mediated nephritis; immune-mediated uveitis; panic attack; pituitary disorder; respiratory disorders; tinnitus Side-effects, further information Immune-mediated adverse reactions can be delayed and have occurred up to 3 to 4 months after the last dose of treatment.
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Clinical governance
**Author:** MedNext Clinical Team. **Clinical reviewer:** Dr Shameer Deen, MBBS, MS, MRCS. **Sources:** BNF, Indian Pharmacopoeia, CIMS India. **Correction:** Report errors at support@mednext.academy.
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