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Saxagliptin with dapagliflozin: Indications, Dosing, Side Effects and Interactions
Saxagliptin with dapagliflozin clinical drug profile including indications, dosing, side effects, cautions and interactions.
MedNext Academy | 3 min read
Saxagliptin with dapagliflozin: Indications, Dosing, Side Effects and Interactions
Saxagliptin with dapagliflozin clinical drug profile including indications, dosing, side effects, cautions and interactions.
Indications and dose
**Type 2 diabetes mellitus not controlled by metformin and/or a sulfonylurea with either saxagliptin or dapagliflozin**
- **Adult** (By Mouth): 75 years and over Initiation not recommended.
Hepatic impairment
For saxagliptin with dapagliflozin Manufacturer advises caution in moderate impairment; avoid in severe impairment.
Renal impairment
For saxagliptin with dapagliflozin Dose adjustments Manufacturer advises avoid if eGFR less than 60 mL/minute/1.73 m 2 (ineffective).
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Clinical governance
**Author:** MedNext Clinical Team. **Clinical reviewer:** Dr Shameer Deen, MBBS, MS, MRCS. **Sources:** BNF, Indian Pharmacopoeia, CIMS India. **Correction:** Report errors at support@mednext.academy.
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