Formulary
Salicylic acid: Indications, Dosing, Side Effects and Interactions
Salicylic acid clinical drug profile including indications, dosing, side effects, cautions and interactions.
MedNext Academy | 3 min read
Salicylic acid: Indications, Dosing, Side Effects and Interactions
Salicylic acid clinical drug profile including indications, dosing, side effects, cautions and interactions.
Indications and dose
**Common and plantar warts for Occlusal**
- **Child** (To the lesion): Apply daily, treatment may need to be continued for up to 3 months.
**For plantar warts for Verrugon**
- **Child** (To the lesion): Apply daily, treatment may need to be continued for up to 3 months.
Cautions
Application to large areas; avoid broken skin; impaired peripheral circulation; not suitable for application to anogenital region; not suitable for application to face; patients with diabetes at risk of neuropathic ulcers; severe peripheral neuropathy Cautions, further information Application to large areas and salicylate toxicity Salicylate toxicity may occur particularly if applied on large areas of skin or neonatal skin.
Side effects
Frequency not known Skin irritation
Interactions
**Other interactions (6):**
- The enzyme dihydropyrimidine dehydrogenase (DPD) plays an important role in the breakdown of fluorouracil.
- Antiviral nucleoside analogues such as brivudine and sorivudine may lead to a drastic increase in plasma concentrations of fluorouracil or other fluoropyrimidines and thus an associated increase in...
- For this reason, an interval of at least 4 weeks between the use of fluorouracil and brivudine, sorivudine and analogues should be observed.
- In case of accidental administration of nucleoside analogues such as brivudine and sorivudine to patients who are being treated with fluorouracil, effective measures for reducing fluorouracil...
- Elevated plasma levels of phenytoin leading to symptoms of phenytoin intoxication have been reported with the concomitant administration of systemic fluorouracil and phenytoin.
- There is no evidence for relevant systemic absorption of salicylic acid, however absorbed salicylic acid may interact with methotrexate and sulphonylureas.
Medicinal forms
Ointment,Ointment,Solution
Clinical governance
**Author:** MedNext Clinical Team. **Clinical reviewer:** Dr Shameer Deen, MBBS, MS, MRCS. **Sources:** BNF, Indian Pharmacopoeia, CIMS India. **Correction:** Report errors at support@mednext.academy.
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