Formulary
Ripretinib [Specialist drug]: Indications, Dosing, Side Effects and Interactions
Ripretinib [Specialist drug] clinical drug profile including indications, dosing, side effects, cautions and interactions.
MedNext Academy | 3 min read
Ripretinib [Specialist drug]: Indications, Dosing, Side Effects and Interactions
Ripretinib [Specialist drug] clinical drug profile including indications, dosing, side effects, cautions and interactions.
Indications and dose
**Gastro-intestinal stromal tumour**
- **Adult** (By Mouth): Specialist drug - access specialist resources for dosing information.
Contraindications
For ripretinib [Specialist drug] Hypertension (do not initiate unless blood pressure adequately controlled)
Side effects
For ripretinib [Specialist drug] Common or very common Alopecia; arthralgia; constipation; cough; depression; diarrhoea; diastolic dysfunction; dyspnoea; fatigue; gastrointestinal discomfort; headache; heart failure; hypertension; hypophosphataemia; hypothyroidism; muscle complaints; muscle weakness; nausea; neoplasms; pain; peripheral neuropathy; peripheral oedema; skin reactions; stomatitis; tachycardia; vomiting; weight decreased Frequency not known Anaemia Side-effects, further information Permanently discontinue treatment if grade 3 or 4 left ventricular systolic dysfunction occurs. If hypertension occurs, withhold treatment or permanently discontinue.
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Clinical governance
**Author:** MedNext Clinical Team. **Clinical reviewer:** Dr Shameer Deen, MBBS, MS, MRCS. **Sources:** BNF, Indian Pharmacopoeia, CIMS India. **Correction:** Report errors at support@mednext.academy.
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