Formulary
Regorafenib [Specialist drug]: Indications, Dosing, Side Effects and Interactions
Regorafenib [Specialist drug] clinical drug profile including indications, dosing, side effects, cautions and interactions.
MedNext Academy | 3 min read
Regorafenib [Specialist drug]: Indications, Dosing, Side Effects and Interactions
Regorafenib [Specialist drug] clinical drug profile including indications, dosing, side effects, cautions and interactions.
Indications and dose
**Colorectal cancer,Gastrointestinal stromal tumours,Hepatocellular carcinoma**
- **Adult** (By Mouth): Specialist drug - access specialist resources for dosing information.
Side effects
For regorafenib [Specialist drug] Common or very common Alopecia; anaemia; appetite decreased; asthenia; diarrhoea; dry mouth; dysphonia; electrolyte imbalance; fever; gastrooesophageal reflux disease; haemorrhage; headache; hyperbilirubinaemia; hypertension; hyperuricaemia; hypothyroidism; increased risk of infection; leucopenia; mucositis; musculoskeletal stiffness; nausea; pain; proteinuria; skin reactions; stomatitis; taste altered; thrombocytopenia; tremor; vomiting; weight decreased Uncommon Gastrointestinal fistula (discontinue); gastrointestinal perforation (including fatal cases, discontinue); hepatic disorders; myocardial infarction (withhold treatment); myocardial ischaemia (withhold treatment); nail disorder Rare or very rare Neoplasms; posterior reversible encephalopathy syndrome (PRES) (discontinue); severe cutaneous adverse reactions (SCARs) Frequency not known Aneurysm; artery dissection
Medicinal forms
Clinical governance
**Author:** MedNext Clinical Team. **Clinical reviewer:** Dr Shameer Deen, MBBS, MS, MRCS. **Sources:** BNF, Indian Pharmacopoeia, CIMS India. **Correction:** Report errors at support@mednext.academy.
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