Formulary
Ramucirumab [Specialist drug]: Indications, Dosing, Side Effects and Interactions
Ramucirumab [Specialist drug] clinical drug profile including indications, dosing, side effects, cautions and interactions.
MedNext Academy | 3 min read
Ramucirumab [Specialist drug]: Indications, Dosing, Side Effects and Interactions
Ramucirumab [Specialist drug] clinical drug profile including indications, dosing, side effects, cautions and interactions.
Indications and dose
**Gastric cancer,Colorectal cancer,Non-small cell lung cancer,Hepatocellular carcinoma**
- **Adult** (By Intravenous Infusion): Specialist drug - access specialist resources for dosing information.
Side effects
For ramucirumab [Specialist drug] Common or very common Arterial thromboembolism; diarrhoea; electrolyte imbalance; encephalopathy; epistaxis; gastrointestinal discomfort; gastrointestinal disorders; headache; hepatic coma; hepatic pain; hypertension; hypoalbuminaemia; infusion related reaction; nephrotic syndrome; neutropenia; peripheral oedema; proteinuria; rash; thrombocytopenia Frequency not known Aneurysm; artery dissection; cardiac arrest; cerebrovascular insufficiency; haemangioma; myocardial infarction; thrombotic microangiopathy Side-effects, further information Infusion-related hypersensitivity reactions have been reported with ramucirumab, particularly during or following the first or second infusion-if the patient experiences a grade 1 or 2 infusion-related reaction, the manufacturer advises to reduce rate of infusion and give premedication for all subsequent infusions; permanently discontinue treatment in grade 3 or 4 infusion-related reactions.
Medicinal forms
Clinical governance
**Author:** MedNext Clinical Team. **Clinical reviewer:** Dr Shameer Deen, MBBS, MS, MRCS. **Sources:** BNF, Indian Pharmacopoeia, CIMS India. **Correction:** Report errors at support@mednext.academy.
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