Formulary
Rabies immunoglobulin: Indications, Dosing, Side Effects and Interactions
Rabies immunoglobulin clinical drug profile including indications, dosing, side effects, cautions and interactions.
MedNext Academy | 3 min read
Rabies immunoglobulin: Indications, Dosing, Side Effects and Interactions
Rabies immunoglobulin clinical drug profile including indications, dosing, side effects, cautions and interactions.
Indications and dose
**Post-exposure treatment against rabies infection for rabies immunoglobulin**
- **Child** (By local infiltration, or by intramuscular injection): 20 units/kg, dose administered by infiltration in and around the cleansed wound; if wound not visible or healed or if infiltration of whole volume not possible, give remainder by intramuscular injection into anterolateral thigh (remote from vaccination site). If more than 2 mL to be given by intramuscular injection then give in divided doses at different sites, to be given in combination with rabies vaccine, not required if more than 7 days have elapsed after the first dose of vaccine, or more than 1 day after the second dose of vaccine.
Cautions
IgA deficiency; interference with live virus vaccines
Side effects
Rare or very rare Arthralgia; chills; fatigue; fever; headache; hypersensitivity; hypotension; influenza like illness; malaise; nausea; skin reactions; tachycardia; vomiting
Medicinal forms
Clinical governance
**Author:** MedNext Clinical Team. **Clinical reviewer:** Dr Shameer Deen, MBBS, MS, MRCS. **Sources:** BNF, Indian Pharmacopoeia, CIMS India. **Correction:** Report errors at support@mednext.academy.
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