Formulary
Pertuzumab [Specialist drug]: Indications, Dosing, Side Effects and Interactions
Pertuzumab [Specialist drug] clinical drug profile including indications, dosing, side effects, cautions and interactions.
MedNext Academy | 3 min read
Pertuzumab [Specialist drug]: Indications, Dosing, Side Effects and Interactions
Pertuzumab [Specialist drug] clinical drug profile including indications, dosing, side effects, cautions and interactions.
Indications and dose
**Breast cancer**
- **Adult** (By Intravenous Infusion): Specialist drug - access specialist resources for dosing information.
Side effects
For pertuzumab [Specialist drug] Common or very common With parenteral use Alopecia; anaemia; appetite decreased; arthralgia; asthenia; chills; constipation; cough; diarrhoea; dizziness; dyspnoea; epistaxis; excessive tearing; fever; gastrointestinal discomfort; headache; hot flush; hypersensitivity; increased risk of infection; infusion related reaction; insomnia; left ventricular dysfunction; leucopenia; mucositis; myalgia; nail disorder; nausea; neutropenia; oedema; pain; paraesthesia; peripheral neuropathy; skin reactions; stomatitis; taste altered; vomiting Uncommon With parenteral use Heart failure; interstitial lung disease; pleural effusion Rare or very rare With parenteral use Cytokine release syndrome; tumour lysis syndrome Frequency not known With parenteral use Hypomagnesaemia; neutropenic sepsis; weight decreased Side-effects, further information Side-effects mostly described for pertuzumab in combination with other antineoplastic drugs. Heart failure Withhold treatment if signs and symptoms suggestive of congestive heart failure occur; discontinue treatment if symptomatic heart failure confirmed.
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Clinical governance
**Author:** MedNext Clinical Team. **Clinical reviewer:** Dr Shameer Deen, MBBS, MS, MRCS. **Sources:** BNF, Indian Pharmacopoeia, CIMS India. **Correction:** Report errors at support@mednext.academy.
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