Formulary
Pentosan polysulfate sodium: Indications, Dosing, Side Effects and Interactions
Pentosan polysulfate sodium clinical drug profile including indications, dosing, side effects, cautions and interactions.
MedNext Academy | 3 min read
Pentosan polysulfate sodium: Indications, Dosing, Side Effects and Interactions
Pentosan polysulfate sodium clinical drug profile including indications, dosing, side effects, cautions and interactions.
Indications and dose
**Bladder pain syndrome**
- **Adult** (By Mouth): 100 mg 3 times a day, review treatment after 6 months and discontinue if no response.
Cautions
For pentosan polysulfate sodium Patients at increased risk of bleeding
Contraindications
For pentosan polysulfate sodium Active bleeding
Side effects
For pentosan polysulfate sodium Common or very common Alopecia; asthenia; back pain; diarrhoea; dizziness; gastrointestinal discomfort; haemorrhage; headache; increased risk of infection; nausea; pelvic pain; peripheral oedema Uncommon Amblyopia; anaemia; appetite decreased; arthralgia; constipation; depression; dyspnoea; emotional lability; eye disorders; flatulence; hyperhidrosis; hyperkinesia; insomnia; leucopenia; melanocytic naevus size increased; myalgia; oral ulceration; paraesthesia; photosensitivity reaction; skin reactions; thrombocytopenia; tinnitus; vomiting; weight changes Frequency not known Coagulation disorder; hepatic function abnormal
Pregnancy
For pentosan polysulfate sodium Manufacturer advises avoid-no information available.
Breast feeding
For pentosan polysulfate sodium Manufacturer advises avoid-no information available.
Hepatic impairment
For pentosan polysulfate sodium Manufacturer advises caution-evidence of hepatic involvement in elimination.
Renal impairment
For pentosan polysulfate sodium Manufacturer advises caution-evidence of renal involvement in elimination.
Medicinal forms
Clinical governance
**Author:** MedNext Clinical Team. **Clinical reviewer:** Dr Shameer Deen, MBBS, MS, MRCS. **Sources:** BNF, Indian Pharmacopoeia, CIMS India. **Correction:** Report errors at support@mednext.academy.
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