Formulary
Panitumumab [Specialist drug]: Indications, Dosing, Side Effects and Interactions
Panitumumab [Specialist drug] clinical drug profile including indications, dosing, side effects, cautions and interactions.
MedNext Academy | 3 min read
Panitumumab [Specialist drug]: Indications, Dosing, Side Effects and Interactions
Panitumumab [Specialist drug] clinical drug profile including indications, dosing, side effects, cautions and interactions.
Indications and dose
**Colorectal cancer**
- **Adult** (By Intravenous Infusion): Specialist drug - access specialist resources for dosing information.
Contraindications
For panitumumab [Specialist drug] Interstitial pulmonary disease; the combination of panitumumab with oxaliplatin-containing chemotherapy is contra-indicated in patients with mutant RAS metastatic colorectal cancer or for whom RAS status is unknown
Side effects
For panitumumab [Specialist drug] Common or very common Alopecia; anaemia; anxiety; appetite decreased; asthenia; chest pain; chills; constipation; cough; dehydration; diarrhoea; dizziness; dry eye; dry mouth; dyspnoea; electrolyte imbalance; embolism and thrombosis; eye discomfort; eye disorders; eye inflammation; fever; flushing; gastrointestinal discomfort; gastrooesophageal reflux disease; haemorrhage; hair changes; headache; hyperglycaemia; hyperhidrosis; hypersensitivity (may be delayed); hypertension; hypotension; increased risk of infection; insomnia; leucopenia; mucositis; nail disorders; nausea; oral disorders; pain; peripheral oedema; skin reactions; skin ulcer; tachycardia; vomiting; weight decreased Uncommon Angioedema; bronchospasm; cyanosis; infusion related reaction; nasal dryness; onycholysis; severe cutaneous adverse reactions (SCARs) Rare or very rare Anaphylactic reaction Frequency not known Interstitial lung disease
Medicinal forms
Clinical governance
**Author:** MedNext Clinical Team. **Clinical reviewer:** Dr Shameer Deen, MBBS, MS, MRCS. **Sources:** BNF, Indian Pharmacopoeia, CIMS India. **Correction:** Report errors at support@mednext.academy.
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