Formulary
Nystatin: Indications, Dosing, Side Effects and Interactions
Nystatin clinical drug profile including indications, dosing, side effects, cautions and interactions.
MedNext Academy | 3 min read
Nystatin: Indications, Dosing, Side Effects and Interactions
Nystatin clinical drug profile including indications, dosing, side effects, cautions and interactions.
Indications and dose
**Oral candidiasis for nystatin**
- **Neonate** (By oromucosal administration): 100 000 units 4 times a day usually for 7 days, and continued for 48 hours after lesions have resolved, to be given after feeds.
- **Child** (By oromucosal administration): 100 000 units 4 times a day usually for 7 days, and continued for 48 hours after lesions have resolved.
**Oral and perioral fungal infections (dose approved for use by community practitioner nurse prescribers) for nystatin**
- **Neonate** (By oromucosal administration): 100 000 units 4 times a day usually for 7 days, and continued for 48 hours after lesions have resolved, to be given after feeds.
- **Child** (By oromucosal administration): 100 000 units 4 times a day usually for 7 days, and continued for 48 hours after lesions have resolved.
Side effects
Frequency not known Abdominal distress; angioedema; diarrhoea; face oedema; nausea; sensitisation; skin reactions; Stevens-Johnson syndrome; vomiting
Interactions
**Other interactions (3):**
- CYP3A4 inhibitors Co-administered drugs that can inhibit CYP3A4 (e.g.
- The extent to which this interaction is clinically relevant depends on the dose and route of administration of the corticosteroids and the potency of the CYP3A4 inhibitor.
- No hazardous interactions have been reported with use of clobetasol propionate or nystatin.
Medicinal forms
Suspension
Clinical governance
**Author:** MedNext Clinical Team. **Clinical reviewer:** Dr Shameer Deen, MBBS, MS, MRCS. **Sources:** BNF, Indian Pharmacopoeia, CIMS India. **Correction:** Report errors at support@mednext.academy.
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