Formulary
Neratinib [Specialist drug]: Indications, Dosing, Side Effects and Interactions
Neratinib [Specialist drug] clinical drug profile including indications, dosing, side effects, cautions and interactions.
MedNext Academy | 3 min read
Neratinib [Specialist drug]: Indications, Dosing, Side Effects and Interactions
Neratinib [Specialist drug] clinical drug profile including indications, dosing, side effects, cautions and interactions.
Indications and dose
**Breast cancer**
- **Adult** (By Mouth): Specialist drug - access specialist resources for dosing information.
Side effects
For neratinib [Specialist drug] Common or very common Appetite decreased; dehydration; diarrhoea; dry mouth; epistaxis; fatigue; gastrointestinal discomfort; increased risk of infection; mucositis; muscle spasms; nail discolouration; nail disorders; nausea; oral disorders; skin reactions; vomiting; weight decreased Uncommon Renal failure Frequency not known Hepatotoxicity Side-effects, further information Diarrhoea Diarrhoea can be severe and associated with dehydration; it is more likely to occur during initiation and can be recurrent. Diarrhoea should be managed appropriately by anti-diarrhoeal treatment, interruption or discontinuation of treatment, dose modifications, and dietary changes. An anti-diarrhoeal should be initiated with the first dose, and maintained during the first 1 to 2 months of treatment, aiming for 1 to 2 bowel motions per day. Hepatotoxicity If hepatotoxicity occurs, manufacturer advises treatment should be withheld or permanently discontinued, based on severity.
Medicinal forms
Clinical governance
**Author:** MedNext Clinical Team. **Clinical reviewer:** Dr Shameer Deen, MBBS, MS, MRCS. **Sources:** BNF, Indian Pharmacopoeia, CIMS India. **Correction:** Report errors at support@mednext.academy.
Inside MedNext for this topic
- 411 MedNext-authored chapters
- 80,000+ MCQ bank
- 15 study modes
- Growing visual cheat sheets
Study modes
- Notes
- MCQ
- Audio
- Video
- Visual
- 3D Anatomy
- Trace
- Flashcards
- Mnemonics
- Image Bank
- Clinical
- Microscopy
- Audio QBank
- Cadaver
- Book Match
Continue reading
Subject HubPharmacology Hub
All pharmacology resources in one place.
Drug SchedulesIndian Drug Schedules
Schedule H, H1, X and G classifications.
FormularyBrowse all drugs
Search 1,850+ drug profiles.
Study Neratinib [Specialist drug] in the MedNext app
Challenge yourself with targeted pharmacology MCQs on this drug class. Every explanation links back to the chapter that teaches the concept.
Start drug challengeExplore the full formulary

