Formulary
Mizolastine: Indications, Dosing, Side Effects and Interactions
Mizolastine clinical drug profile including indications, dosing, side effects, cautions and interactions.
MedNext Academy | 3 min read
Mizolastine: Indications, Dosing, Side Effects and Interactions
Mizolastine clinical drug profile including indications, dosing, side effects, cautions and interactions.
Indications and dose
**Symptomatic relief of allergy such as hay fever, urticaria**
- **Child** (By Mouth): 12-17 years 10 mg once daily.
- **Adult** (By Mouth): 10 mg once daily.
**Symptomatic relief of allergy such as hay fever, urticaria for mizolastine**
- **Child 12-17 years** (By mouth): 10 mg once daily.
Contraindications
Cardiac disease; susceptibility to QT-interval prolongation
Side effects
Common or very common Appetite increased; asthenia; diarrhoea; dizziness; drowsiness; dry mouth; gastrointestinal discomfort; headache; nausea; weight increased Uncommon Anxiety; arrhythmias; arthralgia; depression; myalgia; palpitations Rare or very rare Hypersensitivity Frequency not known Asthma exacerbated; bronchospasm; QT interval prolongation Side-effects, further information Non-sedating antihistamines such as mizolastine cause less sedation and psychomotor impairment than the older antihistamines, but can still occur; sedation is generally minimal. This is because non-sedating antihistamines penetrate the blood brain barrier to a much lesser extent.
Interactions
**Other interactions (6):**
- Antihistamines: Increased risk of ventricular arrhythmias with mizolastine, astemizole and terfenadine (avoid concomitant use).
- Medicinal products affected by serum potassium disturbances Periodic monitoring of serum potassium and ECG is recommended when olmesartan/hydrochlorothiazide is administered with medicinal products...
- Combinations requiring precautions for use Torsades de pointes-inducing drugs (such as but not limited to): class Ia antiarrhythmics agents ( e.g.quinidine, hydroquinidine, disopyramide), class...
- Combined therapy with the following drugs which prolong the QT interval is contra-indicated (see section 4.3) due to the increased risk of torsades de pointes; for example: Class Ia...
- Examples of such drugs include certain antihistamines (e.g.
- Therefore, co-administration of fluoxetine with medicinal products that prolong the QT interval, such as Class IA and III antiarrhythmics, antipsychotics (e.g.
Pregnancy
Most manufacturers of antihistamines advise avoiding their use during pregnancy; however, there is no evidence of teratogenicity.
Breast feeding
Most antihistamines are present in breast milk in varying amounts; although not known to be harmful, most manufacturers advise avoiding their use in mothers who are breast-feeding.
Hepatic impairment
Manufacturer advises avoid in significant impairment.
Medicinal forms
Medicinal forms No licensed medicines listed.
Clinical governance
**Author:** MedNext Clinical Team. **Clinical reviewer:** Dr Shameer Deen, MBBS, MS, MRCS. **Sources:** BNF, Indian Pharmacopoeia, CIMS India. **Correction:** Report errors at support@mednext.academy.
Inside MedNext for this topic
- 411 MedNext-authored chapters
- 80,000+ MCQ bank
- 15 study modes
- Growing visual cheat sheets
Study modes
- Notes
- MCQ
- Audio
- Video
- Visual
- 3D Anatomy
- Trace
- Flashcards
- Mnemonics
- Image Bank
- Clinical
- Microscopy
- Audio QBank
- Cadaver
- Book Match
Continue reading
Subject HubPharmacology Hub
All pharmacology resources in one place.
Drug SchedulesIndian Drug Schedules
Schedule H, H1, X and G classifications.
FormularyBrowse all drugs
Search 1,850+ drug profiles.
Study Mizolastine in the MedNext app
Challenge yourself with targeted pharmacology MCQs on this drug class. Every explanation links back to the chapter that teaches the concept.
Start drug challengeExplore the full formulary

