Formulary
Mitotane [Specialist drug]: Indications, Dosing, Side Effects and Interactions
Mitotane [Specialist drug] clinical drug profile including indications, dosing, side effects, cautions and interactions.
MedNext Academy | 3 min read
Mitotane [Specialist drug]: Indications, Dosing, Side Effects and Interactions
Mitotane [Specialist drug] clinical drug profile including indications, dosing, side effects, cautions and interactions.
Indications and dose
**Adrenocortical carcinoma**
- **Adult** (By Mouth): Specialist drug - access specialist resources for dosing information.
Contraindications
For mitotane [Specialist drug] Acute porphyrias
Side effects
For mitotane [Specialist drug] Common or very common Adrenal insufficiency; anaemia; appetite decreased; asthenia; cognitive impairment; confusion; diarrhoea; dizziness; drowsiness; dyslipidaemia; gastrointestinal discomfort; gynaecomastia; headache; hepatic disorders; leucopenia; movement disorders; mucositis; muscle weakness; nausea; paraesthesia; polyneuropathy; rash; thrombocytopenia; vertigo; vomiting Frequency not known Encephalopathy; eye disorders; flushing; fungal infection; generalised pain; growth retardation; haemorrhage; hyperpyrexia; hypersalivation; hypertension; hypothyroidism; hypouricaemia; lens opacity; neuro-psychological retardation; ovarian cyst; postural hypotension; proteinuria; taste altered; thyroid disorder; vision disorders
Medicinal forms
Clinical governance
**Author:** MedNext Clinical Team. **Clinical reviewer:** Dr Shameer Deen, MBBS, MS, MRCS. **Sources:** BNF, Indian Pharmacopoeia, CIMS India. **Correction:** Report errors at support@mednext.academy.
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