Formulary
Mifepristone and misoprostol: Indications, Dosing, Side Effects and Interactions
Mifepristone and misoprostol clinical drug profile including indications, dosing, side effects, cautions and interactions.
MedNext Academy | 3 min read
Mifepristone and misoprostol: Indications, Dosing, Side Effects and Interactions
Mifepristone and misoprostol clinical drug profile including indications, dosing, side effects, cautions and interactions.
Indications and dose
**Medical termination of intra-uterine pregnancy of up to 63 days gestation (under close medical supervision)**
- **Adult** (By Mouth, Or By Vagina): (consult product literature).
Side effects
For mifepristone and misoprostol Common or very common Diarrhoea; gastrointestinal discomfort; haemorrhage; nausea; uterine disorders; vomiting Uncommon Infection; skin reactions Rare or very rare Chills; dizziness; erythema nodosum; fever; headache; hot flush; hypotension; malaise; severe cutaneous adverse reactions (SCARs); uterine rupture Frequency not known Cardiac arrest; cardiovascular event; coronary vasospasm; myocardial infarction; pelvic inflammatory disease; toxic shock syndrome
Pregnancy
Medical termination of intra-uterine pregnancy of up to 63 days gestation (under close medical supervision) for mifepristone and misoprostol By mouth, or by vagina Adult (consult product literature).
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Clinical governance
**Author:** MedNext Clinical Team. **Clinical reviewer:** Dr Shameer Deen, MBBS, MS, MRCS. **Sources:** BNF, Indian Pharmacopoeia, CIMS India. **Correction:** Report errors at support@mednext.academy.
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