Formulary
Menotrophin: Indications, Dosing, Side Effects and Interactions
Menotrophin is purified extract of human post-menopausal urine containing follicle-stimulating hormone (FSH) and luteinising hormone (LH) in a ratio of 1:1.
MedNext Academy | 3 min read
Menotrophin: Indications, Dosing, Side Effects and Interactions
Menotrophin is purified extract of human post-menopausal urine containing follicle-stimulating hormone (FSH) and luteinising hormone (LH) in a ratio of 1:1.
Drug action
Menotrophin is purified extract of human post-menopausal urine containing follicle-stimulating hormone (FSH) and luteinising hormone (LH) in a ratio of 1:1.
Indications and dose
**Infertility in women with proven hypopituitarism or who have not responded to clomifene,Superovulation treatment**
- **Adult** (By Subcutaneous Injection, Or By Deep Intramuscular Injection): for assisted conception (such as in vitro fertilisation) (female) Adjusted according to response.
**Hypogonadotrophic hypogonadism**
- **Adult** (By Deep Intramuscular Injection, Or By Subcutaneous Injection): (male) (consult product literature).
Cautions
Acute porphyrias ; history of tubal disease
Contraindications
Ovarian cysts (not caused by polycystic ovarian syndrome); ovarian enlargement (not caused by polycystic ovarian syndrome); tumours of breast; tumours of hypothalamus; tumours of ovaries; tumours of pituitary; tumours of prostate; tumours of testes; tumours of uterus; vaginal bleeding of unknown cause
Side effects
Common or very common Gastrointestinal discomfort; headache; nausea; ovarian and fallopian tube disorders; pelvic pain; uterine pain Uncommon Breast abnormalities; diarrhoea; dizziness; fatigue; hot flush; vomiting Rare or very rare Skin reactions Frequency not known Arthralgia; pain; thromboembolism; vision disorder
Pregnancy
Avoid.
Breast feeding
Avoid.
Medicinal forms
Clinical governance
**Author:** MedNext Clinical Team. **Clinical reviewer:** Dr Shameer Deen, MBBS, MS, MRCS. **Sources:** BNF, Indian Pharmacopoeia, CIMS India. **Correction:** Report errors at support@mednext.academy.
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