Formulary
Mebendazole: Indications, Dosing, Side Effects and Interactions
Mebendazole clinical drug profile including indications, dosing, side effects, cautions and interactions.
MedNext Academy | 3 min read
Mebendazole: Indications, Dosing, Side Effects and Interactions
Mebendazole clinical drug profile including indications, dosing, side effects, cautions and interactions.
Indications and dose
**Threadworm infections**
- **Child** (By Mouth): 6 months-17 years 100 mg for 1 dose, if reinfection occurs, second dose may be needed after 2 weeks.
- **Adult** (By Mouth): 100 mg for 1 dose, if reinfection occurs, second dose may be needed after 2 weeks.
**Whipworm infections,Hookworm infections**
- **Child** (By Mouth): 1-17 years 100 mg twice daily for 3 days.
- **Adult** (By Mouth): 100 mg twice daily for 3 days.
**Roundworm infections**
- **Child** (By Mouth): 2-17 years 100 mg twice daily for 3 days, alternatively 500 mg for 1 dose.
- **Adult** (By Mouth): 100 mg twice daily for 3 days, alternatively 500 mg for 1 dose.
**Threadworm infections (dose approved**
- **Child** (By Mouth): for use by community practitioner nurse prescribers) 2-17 years 100 mg for 1 dose, if reinfection occurs, second dose may be needed after 2 weeks.
- **Adult** (By Mouth): 100 mg for 1 dose, if reinfection occurs, second dose may be needed after 2 weeks.
**Threadworm infections for mebendazole**
- **Child 6 months-17 years** (By mouth): 100 mg for 1 dose, if reinfection occurs, second dose may be needed after 2 weeks.
**Whipworm infections, Hookworm infections for mebendazole**
- **Child 1-17 years** (By mouth): 100 mg twice daily for 3 days.
**Roundworm infections for mebendazole**
- **Child 1 year** (By mouth): 100 mg twice daily for 3 days.
- **Child 2-17 years** (By mouth): 100 mg twice daily for 3 days, alternatively 500 mg for 1 dose.
**Threadworm infections (dose approved for use by community practitioner nurse prescribers) for mebendazole**
- **Child 2-17 years** (By mouth): 100 mg for 1 dose, if reinfection occurs, second dose may be needed after 2 weeks.
Side effects
Common or very common Gastrointestinal discomfort Uncommon Diarrhoea; flatulence Rare or very rare Alopecia; dizziness; hepatitis; neutropenia; seizure; severe cutaneous adverse reactions (SCARs); skin reactions
Interactions
**Other interactions (2):**
- Concomitant treatment with cimetidine may inhibit the metabolism of mebendazole in the liver, resulting in increased plasma concentrations of the drug.
- Concomitant use of mebendazole and metronidazole should be avoided (see Section 4.4).
Pregnancy
Manufacturer advises avoid-toxicity in animal studies.
Breast feeding
Amount present in milk too small to be harmful but manufacturer advises avoid.
Medicinal forms
Tablet,Suspension
Clinical governance
**Author:** MedNext Clinical Team. **Clinical reviewer:** Dr Shameer Deen, MBBS, MS, MRCS. **Sources:** BNF, Indian Pharmacopoeia, CIMS India. **Correction:** Report errors at support@mednext.academy.
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