Formulary
Lorlatinib [Specialist drug]: Indications, Dosing, Side Effects and Interactions
Lorlatinib [Specialist drug] clinical drug profile including indications, dosing, side effects, cautions and interactions.
MedNext Academy | 3 min read
Lorlatinib [Specialist drug]: Indications, Dosing, Side Effects and Interactions
Lorlatinib [Specialist drug] clinical drug profile including indications, dosing, side effects, cautions and interactions.
Indications and dose
**Non-small cell lung cancer**
- **Adult** (By Mouth): Specialist drug - access specialist resources for dosing information.
Side effects
For lorlatinib [Specialist drug] Common or very common Anaemia; anxiety; arthralgia; asthenia; behaviour abnormal; cognitive disorder; concentration impaired; confusion; constipation; delirium; dementia; depression; diarrhoea; dyslipidaemia; gait abnormal; hallucinations; headache; inflammation; interstitial lung disease; learning disability; memory loss; mental impairment (thought disturbance); mood altered; muscle weakness; myalgia; nausea; nerve disorders; neurotoxicity; oedema; pain; peroneal nerve palsy; sensation abnormal; skin reactions; speech impairment; vision disorders; vitreous floater; weight increased Frequency not known Atrioventricular block Side-effects, further information If worsening respiratory symptoms indicative of interstitial lung disease or pneumonitis (including dyspnoea, cough, and fever)-withhold or permanently discontinue treatment based on severity.
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Clinical governance
**Author:** MedNext Clinical Team. **Clinical reviewer:** Dr Shameer Deen, MBBS, MS, MRCS. **Sources:** BNF, Indian Pharmacopoeia, CIMS India. **Correction:** Report errors at support@mednext.academy.
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