Formulary
Larotrectinib [Specialist drug]: Indications, Dosing, Side Effects and Interactions
Larotrectinib [Specialist drug] clinical drug profile including indications, dosing, side effects, cautions and interactions.
MedNext Academy | 3 min read
Larotrectinib [Specialist drug]: Indications, Dosing, Side Effects and Interactions
Larotrectinib [Specialist drug] clinical drug profile including indications, dosing, side effects, cautions and interactions.
Indications and dose
**Solid tumours**
- **Adult** (By Mouth): Specialist drug - access specialist resources for dosing information.
Side effects
For larotrectinib [Specialist drug] Common or very common Anaemia; constipation; dizziness; fatigue; gait abnormal; leucopenia; muscle weakness; myalgia; nausea; neutropenia; paraesthesia; taste altered; vomiting; weight increased Side-effects, further information Increases in ALT and AST have been reported in patients receiving larotrectinib; withhold treatment or permanently discontinue depending on severity. The majority of ALT and AST increases occurred in the first 3 months of treatment.
Medicinal forms
Capsule,Solution
Clinical governance
**Author:** MedNext Clinical Team. **Clinical reviewer:** Dr Shameer Deen, MBBS, MS, MRCS. **Sources:** BNF, Indian Pharmacopoeia, CIMS India. **Correction:** Report errors at support@mednext.academy.
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