Formulary
Indacaterol: Indications, Dosing, Side Effects and Interactions
Indacaterol clinical drug profile including indications, dosing, side effects, cautions and interactions.
MedNext Academy | 3 min read
Indacaterol: Indications, Dosing, Side Effects and Interactions
Indacaterol clinical drug profile including indications, dosing, side effects, cautions and interactions.
Indications and dose
**Maintenance treatment of chronic obstructive pulmonary disease**
- **Adult** (By Inhalation Of Powder): 150 micrograms once daily, then increased to 300 micrograms once daily.
Cautions
For all beta-2-adrenoceptor agonists, selective Arrhythmias; cardiovascular disease; diabetes (risk of hyperglycaemia and ketoacidosis, especially with intravenous use); hypertension; hyperthyroidism; hypokalaemia; susceptibility to QT-interval prolongation Cautions, further information Hypokalaemia Potentially serious hypokalaemia may result from beta 2 agonist therapy. Particular caution is required in severe asthma or COPD, because this effect may be potentiated by concomitant treatment with theophylline and its derivatives, corticosteroids, diuretics, and by hypoxia. M Cautions For indacaterol Convulsive disorders
Side effects
For all beta-2-adrenoceptor agonists, selective Common or very common Arrhythmias; dizziness; headache; hyperglycaemia; palpitations; tremor Rare or very rare Bronchospasm paradoxical (sometimes severe) Side-effects For indacaterol Common or very common Chest pain; cough; increased risk of infection; muscle complaints; oropharyngeal pain; peripheral oedema; rhinorrhoea; throat irritation Uncommon Diabetes mellitus; hypersensitivity; musculoskeletal pain; myocardial ischaemia; paraesthesia; skin reactions
Pregnancy
For all beta-2-adrenoceptor agonists, selective Inhaled drugs for asthma can be taken as normal during pregnancy. Pregnancy For indacaterol Manufacturer advises use only if potential benefit outweighs risk.
Breast feeding
Manufacturer advises avoid-present in milk in animal studies.
Hepatic impairment
Manufacturer advises caution in severe impairment (no information available).
Medicinal forms
Clinical governance
**Author:** MedNext Clinical Team. **Clinical reviewer:** Dr Shameer Deen, MBBS, MS, MRCS. **Sources:** BNF, Indian Pharmacopoeia, CIMS India. **Correction:** Report errors at support@mednext.academy.
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