Formulary
Idarubicin hydrochloride [Specialist drug]: Indications, Dosing, Side Effects and Interactions
Idarubicin hydrochloride [Specialist drug] clinical drug profile including indications, dosing, side effects, cautions and interactions.
MedNext Academy | 3 min read
Idarubicin hydrochloride [Specialist drug]: Indications, Dosing, Side Effects and Interactions
Idarubicin hydrochloride [Specialist drug] clinical drug profile including indications, dosing, side effects, cautions and interactions.
Indications and dose
**Acute non-lymphocytic leukaemias,Breast cancer**
- **Adult** (By Mouth): Specialist drug - access specialist resources for dosing information.
**Acute leukaemias,Breast cancer**
- **Adult** (By Intravenous Injection): Specialist drug - access specialist resources for dosing information.
Contraindications
For idarubicin hydrochloride [Specialist drug] Previous treatment with maximum cumulative dose of idarubicin or other anthracycline; recent myocardial infarction; severe arrhythmias; severe myocardial insufficiency
Side effects
For idarubicin hydrochloride [Specialist drug] General side-effects: Common or very common Alopecia; anaemia; appetite decreased; arrhythmias; cardiomyopathy; chills; congestive heart failure; diarrhoea; embolism and thrombosis; fever; haemorrhage; headache; increased risk of infection; leucopenia; nausea; neutropenia; skin reactions; stomatitis; thrombocytopenia; urine discolouration; vomiting Uncommon Dehydration; gastrointestinal disorders; hyperuricaemia; leukaemia secondary; myocardial infarction; nail discolouration; sepsis; shock; soft tissue necrosis Rare or very rare Cardiac conduction disorders; cardiac inflammation; flushing; intracranial haemorrhage Frequency not known Bone marrow disorders; tumour lysis syndrome Specific side-effects: Common or very common With intravenous use Abdominal pain; mucosal abnormalities; paraesthesia; radiation injuries With oral use Gastrointestinal discomfort; mucositis; radiation skin sensitivity
Medicinal forms
Clinical governance
**Author:** MedNext Clinical Team. **Clinical reviewer:** Dr Shameer Deen, MBBS, MS, MRCS. **Sources:** BNF, Indian Pharmacopoeia, CIMS India. **Correction:** Report errors at support@mednext.academy.
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