Formulary
Ibrutinib [Specialist drug]: Indications, Dosing, Side Effects and Interactions
Ibrutinib [Specialist drug] clinical drug profile including indications, dosing, side effects, cautions and interactions.
MedNext Academy | 3 min read
Ibrutinib [Specialist drug]: Indications, Dosing, Side Effects and Interactions
Ibrutinib [Specialist drug] clinical drug profile including indications, dosing, side effects, cautions and interactions.
Indications and dose
**Mantle cell lymphoma,Chronic lymphocytic leukaemia,Waldenstrm's macroglobulinaemia**
- **Adult** (By Mouth): Specialist drug - access specialist resources for dosing information.
Side effects
For ibrutinib [Specialist drug] Common or very common Arrhythmias; arthralgia; broken nails; constipation; diarrhoea; dizziness; dyspepsia; fever; haemorrhage; headache; heart failure; hypertension; hyperuricaemia; increased leucocytes; increased risk of infection; interstitial lung disease; muscle spasms; musculoskeletal pain; nausea; neoplasms; neutropenia; peripheral neuropathy; peripheral oedema; sepsis; skin reactions; stomatitis; thrombocytopenia; vision blurred; vomiting Uncommon Angioedema; cardiac arrest; cerebrovascular insufficiency; CNS haemorrhage; hepatic disorders; hepatitis B reactivation; panniculitis; tumour lysis syndrome Rare or very rare Leukostasis syndrome (withhold treatment); Stevens-Johnson syndrome Frequency not known Anaemia; asthenia; haemophagocytic lymphohistiocytosis; progressive multifocal leukoencephalopathy (PML); splenic rupture (on discontinuation)
Medicinal forms
Clinical governance
**Author:** MedNext Clinical Team. **Clinical reviewer:** Dr Shameer Deen, MBBS, MS, MRCS. **Sources:** BNF, Indian Pharmacopoeia, CIMS India. **Correction:** Report errors at support@mednext.academy.
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