Formulary
Gonadorelin: Indications, Dosing, Side Effects and Interactions
Gonadorelin clinical drug profile including indications, dosing, side effects, cautions and interactions.
MedNext Academy | 3 min read
Gonadorelin: Indications, Dosing, Side Effects and Interactions
Gonadorelin clinical drug profile including indications, dosing, side effects, cautions and interactions.
Indications and dose
**Assessment of pituitary function**
- **Adult** (By Subcutaneous Injection, Or By Intravenous Injection): 100 micrograms for 1 dose.
**Assessment of anterior pituitary function, Assessment of delayed puberty for gonadorelin**
- **Child 1-17 years** (By intravenous injection, or by subcutaneous injection): 2.5 micrograms/kg for 1 dose (max. per dose 100 micrograms).
Cautions
Pituitary adenoma
Side effects
Pain; skin reactions; swelling Rare or very rare Abdominal discomfort; bronchospasm; dizziness; eye erythema; flushing; headache; nausea; tachycardia Frequency not known Menorrhagia; sepsis; thrombophlebitis
Interactions
**Other interactions (2):**
- The gonadorelin test should be conducted in the absence of other drugs which directly affect the pituitary secretion of gonadotropins.
- The response to gonadorelin may be blunted by phenothiazines and dopamine antagonists which cause a rise in prolactin.
Pregnancy
Avoid.
Breast feeding
Avoid.
Medicinal forms
Clinical governance
**Author:** MedNext Clinical Team. **Clinical reviewer:** Dr Shameer Deen, MBBS, MS, MRCS. **Sources:** BNF, Indian Pharmacopoeia, CIMS India. **Correction:** Report errors at support@mednext.academy.
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