Formulary
Gelatin: Indications, Dosing, Side Effects and Interactions
Gelatin clinical drug profile including indications, dosing, side effects, cautions and interactions.
MedNext Academy | 3 min read
Gelatin: Indications, Dosing, Side Effects and Interactions
Gelatin clinical drug profile including indications, dosing, side effects, cautions and interactions.
Indications and dose
**Low blood volume in hypovolaemic shock, burns and cardiopulmonary bypass**
- **Adult** (By Intravenous Infusion): Initially 500-1000 mL, use 3.5-4% solution.
**Low blood volume in hypovolaemic shock, burns and cardiopulmonary bypass for gelatin**
- **Child** (By intravenous infusion): Initially 10-20 mL/kilogram, use 3.5-4% solution.
Cautions
Cardiac disease; severe liver disease
Side effects
Rare or very rare Chills; dyspnoea; fever; hyperhidrosis; hypersensitivity; hypertension; hypotension; hypoxia; tachycardia; tremor; urticaria; wheezing
Interactions
**Other interactions (2):**
- Concomitant administration of clarithromycin (500 mg twice daily) and saquinavir (soft gelatin capsules, 1200 mg three times daily) to 12 healthy volunteers resulted in steady-state AUC and Cmax...
- Observations from drug interaction studies using the soft gelatin capsule formulation may not be representative of the effects seen using the saquinavir hard gelatin capsule.
Pregnancy
Manufacturer of Geloplasma advises avoid at the end of pregnancy.
Hepatic impairment
Manufacturers advise avoid preparations that contain lactate (risk of impaired lactate metabolism).
Renal impairment
Use with caution. M
Medicinal forms
Clinical governance
**Author:** MedNext Clinical Team. **Clinical reviewer:** Dr Shameer Deen, MBBS, MS, MRCS. **Sources:** BNF, Indian Pharmacopoeia, CIMS India. **Correction:** Report errors at support@mednext.academy.
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