Formulary
Estradiol with norethisterone: Indications, Dosing, Side Effects and Interactions
Estradiol with norethisterone clinical drug profile including indications, dosing, side effects, cautions and interactions.
MedNext Academy | 3 min read
Estradiol with norethisterone: Indications, Dosing, Side Effects and Interactions
Estradiol with norethisterone clinical drug profile including indications, dosing, side effects, cautions and interactions.
Indications and dose
**Menopausal symptoms in women with a uterus**
- **Adult** (By Mouth): 1 tablet daily for 16 days, white tablet to be taken, starting on day 5 of menstruation (or at any time if cycles have ceased or are infrequent), then 1 tablet daily for 12 days, pink tablet to be taken, subsequent courses repeated without interval.
**Menopausal symptoms**
- **Adult** (By Mouth): 1 tablet daily for 16 days, white tablet to be taken and started on day 1 of menstruation (or at any time if cycles have ceased or are infrequent), then 1 tablet daily for 12 days, green tablet to be taken, subsequent courses are repeated without interval.
**Menopausal symptoms,Osteoporosis prophylaxis**
- **Adult** (By Transdermal Application): Apply 1 patch twice weekly for 2 weeks, Evorel 50 patch to be applied and started within 5 days of onset of menstruation (or at any time if cycles have ceased or are infrequent), then apply 1 patch twice weekly for the following 2 weeks, Evorel Conti patch to be applied, subsequent courses are repeated without interval.
**Menopausal symptoms in women whose last menstrual period occurred over 12 months previously,Osteoporosis prophylaxis**
- **Adult** (By Mouth): 1 tablet daily continuously, to be started at end of scheduled bleed if changing from cyclical HRT.
**Menopausal symptoms in women whose last menstrual period occurred over 18 months previously,Osteoporosis prophylaxis**
- **Adult** (By Transdermal Application): Apply 1 patch twice weekly continuously, to be started at end of scheduled bleed if changing from cyclical HRT.
**Menopausal symptoms in women with a uterus whose last menstrual period occurred over 12 months previously,Osteoporosis prophylaxis in women with a uterus**
- **Adult** (By Mouth): 1 tablet daily continuously, to be started at end of scheduled bleed if changing from cyclical HRT.
**Menopausal symptoms in women whose last menstrual period occurred over 6 months previously,Osteoporosis prophylaxis**
- **Adult** (By Mouth): 1 tablet daily for 12 days, blue tablet to be taken, followed by 1 tablet daily for 10 days, white tablet to be taken, then 1 tablet daily for 6 days, red tablet to be taken, subsequent courses are repeated without interval; start treatment with blue tablet at any time or if changing from cyclical HRT, start treatment the day after finishing previous regimen.
Medicinal forms
Tablet,Patch
Clinical governance
**Author:** MedNext Clinical Team. **Clinical reviewer:** Dr Shameer Deen, MBBS, MS, MRCS. **Sources:** BNF, Indian Pharmacopoeia, CIMS India. **Correction:** Report errors at support@mednext.academy.
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