Formulary
Enfortumab vedotin [Specialist drug]: Indications, Dosing, Side Effects and Interactions
Enfortumab vedotin [Specialist drug] clinical drug profile including indications, dosing, side effects, cautions and interactions.
MedNext Academy | 3 min read
Enfortumab vedotin [Specialist drug]: Indications, Dosing, Side Effects and Interactions
Enfortumab vedotin [Specialist drug] clinical drug profile including indications, dosing, side effects, cautions and interactions.
Indications and dose
**Urothelial carcinoma**
- **Adult** (By Intravenous Infusion): Specialist drug - access specialist resources for dosing information.
Side effects
For enfortumab vedotin [Specialist drug] Common or very common Alopecia; anaemia; appetite decreased; conjunctivitis; diarrhoea; dry eye; fatigue; gait abnormal; hyperglycaemia; infusion related reaction; interstitial lung disease; muscle weakness; nausea; nerve disorders; sensation abnormal; sepsis; skin reactions; stomatitis; taste altered; vomiting; weight decreased Uncommon Motor dysfunction; muscle atrophy; neuralgia; neurotoxicity; peroneal nerve palsy Frequency not known Diabetic ketoacidosis; neutropenia; severe cutaneous adverse reactions (SCARs) Side-effects, further information Hyperglycaemia and diabetic ketoacidosis, including fatal events, have been reported in those with and without pre-existing diabetes mellitus; manufacturer advises treatment should be withheld if blood glucose is more than 13.9 mmol/L.
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Clinical governance
**Author:** MedNext Clinical Team. **Clinical reviewer:** Dr Shameer Deen, MBBS, MS, MRCS. **Sources:** BNF, Indian Pharmacopoeia, CIMS India. **Correction:** Report errors at support@mednext.academy.
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