Formulary
Emtricitabine with tenofovir alafenamide: Indications, Dosing, Side Effects and Interactions
Emtricitabine with tenofovir alafenamide clinical drug profile including indications, dosing, side effects, cautions and interactions.
MedNext Academy | 3 min read
Emtricitabine with tenofovir alafenamide: Indications, Dosing, Side Effects and Interactions
Emtricitabine with tenofovir alafenamide clinical drug profile including indications, dosing, side effects, cautions and interactions.
Indications and dose
**HIV-1 infection in combination with other antiretroviral drugs [doses**
- **Adult** (By Mouth): for 200/10 mg or 200/25 mg tablets] (initiated by a specialist) 1 tablet once daily, tablet strength is dependent on drug regimen-consult product literature.
**Pre-exposure prophylaxis of HIV-1 infection [doses**
- **Adult** (By Mouth): for 200/25 mg tablets] (initiated by a specialist) (male) 1 tablet once daily.
**HIV-1 infection in combination with other antiretroviral drugs [doses for 200/10 mg or 200/25 mg tablets] (initiated by a specialist) for emtricitabine with tenofovir alafenamide**
- **Child 12-17 years (body-weight 35 kg and above)** (By mouth): 1 tablet once daily, tablet strength is dependent on drug regimen-consult product literature.
**Pre-exposure prophylaxis of HIV-1 infection [doses for 200/25 mg tablets] (initiated by a specialist) for emtricitabine with tenofovir alafenamide**
- **Child 12-17 years (body-weight 35 kg and above and male)** (By mouth): 1 tablet once daily.
Side effects
For emtricitabine with tenofovir alafenamide Common or very common Abnormal dreams; diarrhoea; dizziness; fatigue; flatulence; gastrointestinal discomfort; headache; nausea; skin reactions; vomiting Uncommon Anaemia; angioedema; arthralgia Frequency not known Immune reconstitution inflammatory syndrome; nephrotoxicity; osteonecrosis
Hepatic impairment
For emtricitabine with tenofovir alafenamide Caution (increased risk of hepatic side-effects). M
Renal impairment
For emtricitabine with tenofovir alafenamide Avoid if creatinine clearance less than 30 mL/minute (limited information available). M See Prescribing in renal impairment .
Medicinal forms
Clinical governance
**Author:** MedNext Clinical Team. **Clinical reviewer:** Dr Shameer Deen, MBBS, MS, MRCS. **Sources:** BNF, Indian Pharmacopoeia, CIMS India. **Correction:** Report errors at support@mednext.academy.
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