Formulary
Eflornithine: Indications, Dosing, Side Effects and Interactions
An antiprotozoal drug that inhibits the enzyme ornithine decarboxylase in hair follicles.
MedNext Academy | 3 min read
Eflornithine: Indications, Dosing, Side Effects and Interactions
An antiprotozoal drug that inhibits the enzyme ornithine decarboxylase in hair follicles.
Drug action
An antiprotozoal drug that inhibits the enzyme ornithine decarboxylase in hair follicles.
Indications and dose
**Adjunct in the treatment of facial hirsutism in women**
- **Adult** (To The Skin): Apply twice daily, to be applied thinly, discontinue use if no improvement after 4 months of treatment.
Side effects
Common or very common Alopecia; increased risk of infection; paraesthesia; skin reactions Uncommon Face oedema; flushing; hair changes; oral disorders; skin haemorrhage Rare or very rare Skin neoplasm
Pregnancy
Toxicity in animal studies-manufacturer advises avoid.
Breast feeding
Manufacturer advises avoid-no information available.
Medicinal forms
Clinical governance
**Author:** MedNext Clinical Team. **Clinical reviewer:** Dr Shameer Deen, MBBS, MS, MRCS. **Sources:** BNF, Indian Pharmacopoeia, CIMS India. **Correction:** Report errors at support@mednext.academy.
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