Formulary
Dorzolamide: Indications, Dosing, Side Effects and Interactions
Dorzolamide clinical drug profile including indications, dosing, side effects, cautions and interactions.
MedNext Academy | 3 min read
Dorzolamide: Indications, Dosing, Side Effects and Interactions
Dorzolamide clinical drug profile including indications, dosing, side effects, cautions and interactions.
Indications and dose
**Raised intra-ocular pressure in ocular hypertension used alone in patients unresponsive to beta-blockers or if beta-blockers contra-indicated,Open-angle glaucoma used alone in patients unresponsive to beta-blockers or if beta-blockers contra-indicated,Pseudo-exfoliative glaucoma used alone in patients unresponsive to beta-blockers or if beta-blockers contra-indicated**
- **Adult** (To The Eye): Apply 3 times a day.
**Raised intra-ocular pressure in ocular hypertension as adjunct to beta-blocker,Open-angle glaucoma as adjunct to beta-blocker,Pseudo-exfoliative glaucoma as adjunct to beta-blocker**
- **Adult** (To The Eye): Apply twice daily.
**Raised intra-ocular pressure in primary and secondary glaucoma used alone in patients unresponsive to beta-blockers or if beta-blockers contra-indicated for dorzolamide**
- **Child** (To the eye): Apply 3 times a day.
**Raised intra-ocular pressure in primary and secondary glaucoma as adjunct to a beta-blocker for dorzolamide**
- **Child** (To the eye): Apply twice daily.
Cautions
Chronic corneal defects; history of intra-ocular surgery; history of renal calculi; low endothelial cell count; systemic absorption follows topical application
Contraindications
Hyperchloraemic acidosis
Side effects
Common or very common Asthenia; eye discomfort; eye disorders; eye inflammation; headache; nausea; taste bitter; vision disorders Rare or very rare Angioedema; bronchospasm; dizziness; dry mouth; dyspnoea; epistaxis; local reaction; paraesthesia; severe cutaneous adverse reactions (SCARs); skin reactions; throat irritation; urolithiasis Frequency not known Hypertension; palpitations; tachycardia Side-effects, further information Systemic absorption can cause sulfonamide-like side-effects and may require discontinuation if severe.
Pregnancy
Manufacturer advises avoid-toxicity in animal studies.
Breast feeding
Manufacturer advises avoid-no information available.
Hepatic impairment
Manufacturer advises caution-no information available.
Renal impairment
Avoid if creatinine clearance less than 30 mL/minute. M See Prescribing in renal impairment .
Medicinal forms
Clinical governance
**Author:** MedNext Clinical Team. **Clinical reviewer:** Dr Shameer Deen, MBBS, MS, MRCS. **Sources:** BNF, Indian Pharmacopoeia, CIMS India. **Correction:** Report errors at support@mednext.academy.
Inside MedNext for this topic
- 411 MedNext-authored chapters
- 80,000+ MCQ bank
- 15 study modes
- Growing visual cheat sheets
Study modes
- Notes
- MCQ
- Audio
- Video
- Visual
- 3D Anatomy
- Trace
- Flashcards
- Mnemonics
- Image Bank
- Clinical
- Microscopy
- Audio QBank
- Cadaver
- Book Match
Continue reading
Subject HubPharmacology Hub
All pharmacology resources in one place.
Drug SchedulesIndian Drug Schedules
Schedule H, H1, X and G classifications.
FormularyBrowse all drugs
Search 1,850+ drug profiles.
Study Dorzolamide in the MedNext app
Challenge yourself with targeted pharmacology MCQs on this drug class. Every explanation links back to the chapter that teaches the concept.
Start drug challengeExplore the full formulary

