Formulary
Degarelix: Indications, Dosing, Side Effects and Interactions
Degarelix clinical drug profile including indications, dosing, side effects, cautions and interactions.
MedNext Academy | 3 min read
Degarelix: Indications, Dosing, Side Effects and Interactions
Degarelix clinical drug profile including indications, dosing, side effects, cautions and interactions.
Indications and dose
**Advanced hormone-dependent prostate cancer**
- **Adult** (By Subcutaneous Injection): Initially 240 mg, to be administered as 2 injections of 120 mg, then 80 mg every 28 days, dose to be administered into the abdominal region.
Cautions
Diabetes; susceptibility to QT-interval prolongation
Side effects
Common or very common Anaemia; chills; diarrhoea; dizziness; fatigue; fever; gynaecomastia; headache; hot flush; influenza like illness; insomnia; musculoskeletal discomfort; musculoskeletal pain; nausea; sexual dysfunction; skin reactions; sweat changes; testicular disorders; weight changes Uncommon Alopecia; appetite decreased; arrhythmias; bone disorders; breast pain; cognitive impairment; constipation; depression; diabetes mellitus; dry mouth; dyspnoea; gastrointestinal discomfort; genital discomfort; hyperglycaemia; hypertension; hypotension; joint disorders; malaise; muscle spasms; muscle weakness; numbness; palpitations; pelvic pain; peripheral oedema; QT interval prolongation; renal impairment; urinary disorders; vision blurred; vomiting Rare or very rare Febrile neutropenia; heart failure; injection site necrosis; myocardial infarction; rhabdomyolysis
Hepatic impairment
Manufacturer advises caution (limited information available)-monitor liver function.
Renal impairment
Manufacturer advises caution in severe impairment-no information available.
Medicinal forms
Clinical governance
**Author:** MedNext Clinical Team. **Clinical reviewer:** Dr Shameer Deen, MBBS, MS, MRCS. **Sources:** BNF, Indian Pharmacopoeia, CIMS India. **Correction:** Report errors at support@mednext.academy.
Inside MedNext for this topic
- 411 MedNext-authored chapters
- 80,000+ MCQ bank
- 15 study modes
- Growing visual cheat sheets
Study modes
- Notes
- MCQ
- Audio
- Video
- Visual
- 3D Anatomy
- Trace
- Flashcards
- Mnemonics
- Image Bank
- Clinical
- Microscopy
- Audio QBank
- Cadaver
- Book Match
Continue reading
Subject HubPharmacology Hub
All pharmacology resources in one place.
Drug SchedulesIndian Drug Schedules
Schedule H, H1, X and G classifications.
FormularyBrowse all drugs
Search 1,850+ drug profiles.
Study Degarelix in the MedNext app
Challenge yourself with targeted pharmacology MCQs on this drug class. Every explanation links back to the chapter that teaches the concept.
Start drug challengeExplore the full formulary

