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Cytarabine [Specialist drug]: Indications, Dosing, Side Effects and Interactions
Cytarabine [Specialist drug] clinical drug profile including indications, dosing, side effects, cautions and interactions.
MedNext Academy | 3 min read
Cytarabine [Specialist drug]: Indications, Dosing, Side Effects and Interactions
Cytarabine [Specialist drug] clinical drug profile including indications, dosing, side effects, cautions and interactions.
Indications and dose
**Acute myeloid leukaemia**
- **Adult** (By Intravenous Infusion, Or By Intravenous Injection, Or By Subcutaneous Injection): Specialist drug - access specialist resources for dosing information.
Side effects
For cytarabine [Specialist drug] Common or very common Alopecia; anaemia; appetite decreased; consciousness impaired; diarrhoea; dysarthria; dysphagia; eye disorders; eye inflammation; eye stinging; fever; gastrointestinal discomfort; gastrointestinal disorders; haemorrhagic conjunctivitis (consider prophylactic corticosteroid eye drops); hyperuricaemia; leucopenia; nausea; oral disorders; renal impairment; skin reactions; thrombocytopenia; urinary retention; vasculitis; vision disorders; vomiting Uncommon Arthralgia; dyspnoea; headache; increased risk of infection; myalgia; nerve disorders; pain; paralysis; pericarditis; sepsis; skin ulcer; throat pain Rare or very rare Arrhythmias Frequency not known Acute respiratory distress syndrome (ARDS); amenorrhoea; ataxia; azoospermia; bone marrow disorders; cardiomyopathy; cerebellar dysfunction; chest pain; coma; confusion; cytarabine syndrome; dizziness; drowsiness; haemorrhage; hand and foot syndrome (palmar-plantar erythrodysaesthesia syndrome); hepatic disorders; hyperbilirubinaemia; neurotoxicity; neurotoxicity rash; neutropenia; pancreatitis; personality change; pulmonary oedema; reticulocytopenia; rhabdomyolysis; seizure; tremor
Medicinal forms
Solution
Clinical governance
**Author:** MedNext Clinical Team. **Clinical reviewer:** Dr Shameer Deen, MBBS, MS, MRCS. **Sources:** BNF, Indian Pharmacopoeia, CIMS India. **Correction:** Report errors at support@mednext.academy.
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