Formulary
Cyproheptadine hydrochloride: Indications, Dosing, Side Effects and Interactions
Cyproheptadine hydrochloride clinical drug profile including indications, dosing, side effects, cautions and interactions.
MedNext Academy | 3 min read
Cyproheptadine hydrochloride: Indications, Dosing, Side Effects and Interactions
Cyproheptadine hydrochloride clinical drug profile including indications, dosing, side effects, cautions and interactions.
Indications and dose
**Symptomatic relief of allergy such as hay fever, urticaria,Pruritus**
- **Adult** (By Mouth): 4 mg 3 times a day, usual dose 4-20 mg daily; maximum 32 mg per day.
Cautions
Epilepsy; prostatic hypertrophy; pyloroduodenal obstruction; susceptibility to angle-closure glaucoma; urinary retention
Contraindications
Avoid in Acute porphyrias
Side effects
Frequency not known Aggression; agranulocytosis; anxiety; appetite abnormal; arrhythmias; bronchial secretion viscosity increased; chest tightness; chills; confusion; constipation; coordination abnormal; diarrhoea; dizziness; drowsiness; dry mouth; dry throat; epigastric distress; epistaxis; fatigue; haemolytic anaemia; hallucination; headache; hepatic disorders; hyperhidrosis; hypotension; insomnia; labyrinthitis; leucopenia; menstruation irregular; mood altered; nasal complaints; nausea; neuritis; oedema; palpitations; paraesthesia; photosensitivity reaction; seizure; skin reactions; thrombocytopenia; tinnitus; tremor; urinary disorders; vertigo; vision disorders; vomiting; weight increased; wheezing
Pregnancy
Most manufacturers of antihistamines advise avoiding their use during pregnancy; however, there is no evidence of teratogenicity. Use in the latter part of the third trimester may cause adverse effects in neonates such as irritability, paradoxical excitability, and tremor.
Breast feeding
Most antihistamines are present in breast milk in varying amounts; although not known to be harmful, most manufacturers advise avoiding their use in mothers who are breast-feeding.
Medicinal forms
Solution
Clinical governance
**Author:** MedNext Clinical Team. **Clinical reviewer:** Dr Shameer Deen, MBBS, MS, MRCS. **Sources:** BNF, Indian Pharmacopoeia, CIMS India. **Correction:** Report errors at support@mednext.academy.
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