Formulary
Chlorothiazide: Indications, Dosing, Side Effects and Interactions
Chlorothiazide clinical drug profile including indications, dosing, side effects, cautions and interactions.
MedNext Academy | 3 min read
Chlorothiazide: Indications, Dosing, Side Effects and Interactions
Chlorothiazide clinical drug profile including indications, dosing, side effects, cautions and interactions.
Indications and dose
**Heart failure, Hypertension, Ascites for chlorothiazide**
- **Neonate** (By mouth): 10-20 mg/kg twice daily.
- **Child 1-5 months** (By mouth): 10-20 mg/kg twice daily.
- **Child 6 months-11 years** (By mouth): 10 mg/kg twice daily; maximum 1 g per day.
- **Child 12-17 years** (By mouth): 0.25-1 g once daily, alternatively 125-500 mg twice daily.
**Reduction of diazoxide-induced sodium and water retention in the management of chronic hypoglycaemia, Potentiating the glyacaemic effect of diazoxide in the management of chronic hypoglycaemia for chlorothiazide**
- **Child** (By mouth): 3-5 mg/kg twice daily.
**Nephrogenic and partial pituitary diabetes insipidus for chlorothiazide**
- **Child** (By mouth): 10-20 mg/kg twice daily (max. per dose 500 mg).
Interactions
**Other interactions (2):**
- Colestyramine may delay or reduce the absorption of certain drugs (such as digitalis, tetracycline, chlorothiazide, warfarin and thyroxine).
- Tabulated list of Colestyramine drug-drug interactions: Drug Class Drug(s) Anti-arrhythmics Amiodarone Anti-convulsants Valproate Anti-infectives Vancomycin, tetracycline Antimetabolites...
Clinical governance
**Author:** MedNext Clinical Team. **Clinical reviewer:** Dr Shameer Deen, MBBS, MS, MRCS. **Sources:** BNF, Indian Pharmacopoeia, CIMS India. **Correction:** Report errors at support@mednext.academy.
Inside MedNext for this topic
- 411 MedNext-authored chapters
- 80,000+ MCQ bank
- 15 study modes
- Growing visual cheat sheets
Study modes
- Notes
- MCQ
- Audio
- Video
- Visual
- 3D Anatomy
- Trace
- Flashcards
- Mnemonics
- Image Bank
- Clinical
- Microscopy
- Audio QBank
- Cadaver
- Book Match
Continue reading
Subject HubPharmacology Hub
All pharmacology resources in one place.
Drug SchedulesIndian Drug Schedules
Schedule H, H1, X and G classifications.
FormularyBrowse all drugs
Search 1,850+ drug profiles.
Study Chlorothiazide in the MedNext app
Challenge yourself with targeted pharmacology MCQs on this drug class. Every explanation links back to the chapter that teaches the concept.
Start drug challengeExplore the full formulary

